Sitagliptin Metformin Extended-Release Tablets 5/50/1000 mg (Dapagliflozin, Sitagliptin, Metformin)

Adult dose

The recommended dosage for this medication is 10 mg of dapagliflozin and 100 mg of sitagliptin, with extended-release metformin hydrochloride not exceeding 2000 mg, determined based on each patient’s current treatment regimen, efficacy, and tolerability. To reduce gastrointestinal adverse effects caused by metformin hydrochloride, it should be taken once a day with meals, preferably in the evening.

This medication is used for the treatment of diabetes and helps lower blood sugar levels. However, there are several precautions to consider while taking this medication. First, some components in this medication may cause allergic reactions. If symptoms such as skin rash or shortness of breath occur, discontinue use immediately. Additionally, there is a potential for pancreatitis (inflammation of the pancreas), so if sudden abdominal pain, vomiting, or fever occurs, consult a physician immediately. For patients with impaired renal function or in a state of dehydration, the use of this medication may pose risks, so it's essential to consult a physician before taking it. Patients scheduled for surgery or experiencing severe infections should also temporarily discontinue this medication and resume it only after renal function has returned to normal. This medication may rarely cause serious side effects such as hypoglycemia or lactic acidosis, so if symptoms like dizziness, muscle pain, difficulty in breathing, or abdominal pain arise, visit a medical facility immediately. Furthermore, fluid volume may decrease, leading to lower blood pressure, so elderly individuals or those taking diuretics should exercise caution. Genital infections or urinary tract infections may also occur, so if related symptoms appear, early treatment should be sought. While taking this medication, regular kidney and liver function tests should be conducted, and dosage adjustments or discontinuation should be made when necessary. Finally, alcohol consumption can increase the risk of side effects from this medication, so it is advisable to avoid drinking while on this treatment.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe allergic reactions, severe rash, blisters, peeling skin, pain at mucosal sites (mouth/eyes), severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attack, respiratory distress with cough and fever, respiratory issues, yellowing of the skin or eyes (jaundice), profound lethargy, liver issues (jaundice), sudden and severe symptoms

Mild side effects

• Headache
• hypoglycemia
• vomiting
• diarrhea
• pruritus
• itching
• hives
• rash
• cold sweats
• constipation

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is also advisable to store it at room temperature between 1°C and 30°C, away from extreme heat or cold.

Appearance

Light yellow, double convex, oval-shaped extended-release film-coated tablet

Package unit

30 tablets/bottle