Pharmbio Physiological Saline Injection (Sodium Chloride)

Adult administration

As sodium chloride, typically 20 to 1,000 mL is to be administered subcutaneously, intravenously, by intravenous drip infusion, or rectally. The dose and infusion rate should be adjusted appropriately according to age, weight, and symptoms.

This drug should not be used in patients with hypernatremia. It should also not be administered to patients in a state of fluid overload. This drug should not be administered to patients with cirrhosis accompanied by edema and ascites. It should be used cautiously in patients with cardiovascular or circulatory system dysfunction. Patients with reduced kidney function should also be treated with caution. Care should be taken in patients with hypoproteinemia who have low protein levels in their blood. Caution is required for patients with very low sodium levels in the blood. Attention is also needed for patients with hypokalemia who have low potassium levels in their blood. This drug should be used prudently in patients with hyperchloremia who have high chloride ion concentrations. It should be used carefully in patients with peripheral edema or pulmonary edema. Pregnant women with preeclampsia should also be given special attention. It should be used with caution in patients with conditions related to aldosteronism or sodium excretion, or those undergoing corticosteroid or corticotropin treatment. Extra caution is necessary for pediatric and elderly patients. Rapid or large volume administration of this drug can lead to congestive heart failure, edema, acidosis, and electrolyte imbalances in the blood. Adverse effects such as fever, infection at the injection site, pain, venous irritation, thrombosis, phlebitis, extravasation, and excess blood volume may occur during administration. If adverse effects occur, discontinue administration and assess the patient's condition and provide appropriate treatment. If necessary, the residual solution should be stored for testing. During prolonged non-oral administration of this drug or for patient condition assessment, fluid balance, electrolyte concentration, and acid-base balance should be periodically checked through clinical evaluation and regular laboratory tests. Elderly patients may have reduced physiological functions, so special care should be taken by slowing the infusion rate and reducing the dosage. It must be verified that this drug is suitable for preparation or dilution solutions during compounding. Before administration, always check for color changes, precipitation, insoluble substances, and crystallization. To prevent infection, the patient's skin and the instruments used should be disinfected before administration. In cold seasons, it is preferable to warm this drug to body temperature before use. After opening or adding other medications, it should be used immediately, and any remaining solution should not be used. During administration, slow infusion should be done to minimize the occurrence of adverse effects.

Mild side effects

Fever, infection at the injection site, local pain or reactions, venous irritation, venous thrombosis or phlebitis from the injection site, extravasation, excess blood volume, congestive heart failure, edema, acidosis, serum electrolyte abnormalities

This drug should be stored in a sealed container to prevent air or moisture from entering. The storage temperature should maintain room temperature between 1 and 30 degrees Celsius. This helps to prolong the drug's effectiveness.

Appearance

A colorless, transparent solution contained in a colorless, transparent plastic container for infusion.

Package unit

110 milliliters/pack, 100 milliliters/pack, 60 milliliters/pack, 50 milliliters/pack, 30 milliliters/pack