Daewoong Nisergo-line Tablets 10 mg (Nisergo-line)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 3 times daily before meals. Adjust the dose appropriately according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before meals. If the desired effect is not achieved at this dose, it may be increased to 60 mg. The dose may be reduced after symptoms improve. In patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This medication should not be used in certain patients. For example, individuals allergic to this medication or ergot alkaloids, those with acute myocardial infarction or acute bleeding, individuals taking sympathomimetic drugs, those with a very low heart rate, patients who have not achieved hemostasis after intracranial hemorrhage, and individuals with orthostatic dysregulation should not be administered this drug. It should be used cautiously in patients with mild heart rate reduction or impaired kidney function. When taking this medication, gastrointestinal symptoms such as decreased appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, and dry mouth may occur rarely. Liver function test values may also increase. Cardiovascular abnormal reactions such as dizziness, orthostatic hypotension, increased or decreased blood pressure, and elevated blood uric acid levels may also occur rarely. Mentally, symptoms such as drowsiness, fatigue, headache, tinnitus, and insomnia may occur. Allergic reactions can manifest as skin rash, urticaria, itching, facial flushing, and warmth, so caution is advised. This medication may cause blood pressure to drop too low if taken with other antihypertensive agents, so blood pressure should be monitored frequently. It may affect uric acid metabolism, so patients with a history of gout should be particularly cautious. Caution is needed when driving or operating machinery after taking this drug. This medication is metabolized in the liver, so there may be interactions with other drugs using the same metabolic pathway. Women who are pregnant or may become pregnant should only use this medication when absolutely necessary as its safety has not been established, and those who are breastfeeding should preferably discontinue breastfeeding or avoid taking this medication. Elderly individuals may have decreased physical function, so careful dosage adjustment is required. Safety in children has not yet been confirmed, so use in children should be cautious. In case of overdose, blood pressure may be temporarily lowered, so blood pressure changes should be closely monitored and appropriate measures taken if necessary. This medication should be stored out of reach of children and kept sealed in its original container for safety.

Loss of appetite, diarrhea, constipation, nausea, vomiting, non-specific upper abdominal pain or cramping, dry mouth, ALT elevation, AST elevation, dizziness, orthostatic hypotension, hypertension, increased blood uric acid, blood pressure reduction, drowsiness, fatigue, headache, tinnitus, exhaustion, insomnia, rash, urticaria, itching, flushing, heat sensation, nightmares, mood disturbance, dyspepsia

This medication should be stored in a tightly sealed container that blocks light, preferably at room temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain its effectiveness and prevent deterioration.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle