Medication info
Lipirojet Tablet 10/5 mg (Ezetimibe, Atorvastatin)

Lipirojet Tablet 10/5 mg (Ezetimibe, Atorvastatin)

Prescription medicationTablet경구
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›5.425mg / 1 tablet
Manufacturer / importer
(주)종근당
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 30 tablets/box [(10 tablets/PTP x 3)]
Approval status
Active

MFDS item code 202403092 · Approved 2024.12.27 · Insurance code 643309780

Summary

Main use
Improvement of hypercholesterolemia (primary, mixed) and treatment of dyslipidemia
Who takes it
Adults
Adult dose
This medicine is administered once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/5 mg to 10/80 mg daily. An initial dose of 10/5 mg, 10/10 mg, or 10/20 mg daily is recommended. For patients requiring a greater reduction of LDL cholesterol, an initial dose of 10/40 mg daily is recommended. After starting treatment or adjusting the dosage, lipid levels should be checked at intervals of at least 2 weeks.

Ingredients

Manufacturer
(주)종근당

Efficacy & effects

Improvement of hypercholesterolemia (primary, mixed) and treatment of dyslipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • elevated total cholesterol
  • elevated LDL cholesterol
  • elevated ApoB protein
  • elevated triglycerides
  • elevated non-HDL cholesterol
View approved original text

This medicine helps to lower total cholesterol, LDL cholesterol, ApoB protein, triglycerides, and non-HDL cholesterol levels in patients with primary hypercholesterolemia, particularly heterozygous familial and non-familial cases, or mixed dyslipidemia. It also has the effect of increasing the levels of HDL cholesterol, the good cholesterol, which can improve cardiovascular health. This medicine is used to assist in dietary management, effectively regulating cholesterol levels to help maintain health.

How to take

Adult dose

This medicine is administered once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/5 mg to 10/80 mg daily. An initial dose of 10/5 mg, 10/10 mg, or 10/20 mg daily is recommended. For patients requiring a greater reduction of LDL cholesterol, an initial dose of 10/40 mg daily is recommended. After starting treatment or adjusting the dosage, lipid levels should be checked at intervals of at least 2 weeks.

Precautions

This medicine helps lower blood cholesterol levels. However, if you experience severe muscle pain, weakness, or fatigue during treatment, you should immediately inform your doctor. Especially for individuals after acute infections, major surgeries, or with impaired kidney function, temporary discontinuation of this medicine may be necessary. As this medicine can affect liver function, it is important to undergo liver function tests before and during treatment. If there are liver problems or abnormally high liver enzyme levels, it is advisable not to take this medicine. Women who are pregnant, may become pregnant, or are breastfeeding should not take this medicine, and women of childbearing age should use appropriate contraception during treatment. This medicine may increase the risk of side effects when taken with certain medications, so it is essential to inform your doctor or pharmacist about any other medications you are currently taking. Elderly patients or those with reduced kidney function should also exercise caution when taking this medicine, and any muscle-related symptoms should be reported immediately. Furthermore, dizziness may occur during the use of this medicine, so caution is advised when driving or operating machinery. In case of overdose, seek immediate medical attention for appropriate treatment and monitoring of liver function and muscle status.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest pain, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough+fever, yellowing of skin or eyes (jaundice), profound lethargy, liver abnormalities (jaundice), sudden and very

Mild side effects

  • Headache
  • dizziness
  • paresthesia
  • syncope
  • rhinitis
  • adenovirus infection
  • cystitis
  • milia
  • periodontitis
  • retinitis
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  • indigestion
  • constipation
  • colonic polyps
  • aphthous ulcers
  • pruritus
  • dermatitis
  • dry eyes
  • keratitis
  • macular hole
  • conjunctival injection
  • vitreous floaters
  • weakness
  • chest pain
  • elevation of alanine aminotransferase
  • elevation of aspartate aminotransferase
  • elevation of blood alkaline phosphatase
  • increase in blood pressure

Not everyone experiences these, and they can vary from person to person.

Storage

This medicine should be stored in a tightly sealed container to prevent exposure to air or moisture, at a temperature between 1°C and 30°C. This way of storage helps maintain the efficacy and safety of the medicine.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 30 tablets/box [(10 tablets/PTP x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.