Neuropezil M Tablets 10/20 mg (Donepezil Hydrochloride Hydrate, Memantine Hydrochloride)

Adult dose

For patients who require combination therapy of 10 mg Donepezil Hydrochloride and 20 mg Memantine Hydrochloride, administer 1 tablet of this medication once daily at bedtime, at the same time every day. This medication can be taken regardless of food intake.

This medication should not be used in certain patients. Patients allergic to this medication or its components, those with severe liver or kidney dysfunction, should not use it. It should also not be administered to women who are pregnant or might become pregnant, and to breastfeeding women. Patients with lactose intolerance or genetic metabolic disorders should also refrain from using this medication. Additionally, patients with epilepsy or a history of seizures should use this medication with caution. The use of this medication in conjunction with specific central nervous system drugs may increase side effects, so combination should be avoided. Patients with urinary tract infections or kidney-related diseases should carefully monitor changes in urine pH. Patients with a history of heart disease, hypertension, asthma, etc. should also exercise caution during administration. This medication may cause various side effects, including heart problems, gastrointestinal bleeding, liver dysfunction, neurological symptoms, and muscular issues. Side effects may include dizziness, nausea, vomiting, diarrhea, insomnia, hallucinations, anxiety, muscle cramps, etc. If serious side effects occur, administration should be immediately stopped, and appropriate treatment received. This medication is for patients with Alzheimer's-type dementia, and the therapeutic effects should be regularly evaluated. It is crucial that caregivers closely monitor changes in the patient's condition during treatment. It may affect driving or operating machinery; therefore, particular caution should be exercised, especially in the initial phases of administration. This medication can interact with other drugs; thus, if any other medications are being taken, medical personnel should be informed. Special caution is needed when used with heart-related medications, central nervous system drugs, and nonsteroidal anti-inflammatory drugs. It is safest for pregnant or breastfeeding women to not use this medication, and if absolutely necessary, they should consult healthcare professionals. Safety and effectiveness have not been confirmed in pediatric patients and adolescents under 18 years of age, thus it should not be used. In case of overdose, symptoms such as nausea, vomiting, dizziness, and confusion may occur, and immediate medical attention must be sought. This medication should be kept out of the reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mouth/eyes mucosa, shortness of breath or difficulty breathing, asthma attacks, breathing abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme fatigue, sudden and severe headache, lightning headache, seizures, confusion of consciousness, vision disturbances, paralysis, urination

Mild side effects

• Nausea
• vomiting
• diarrhea
• decreased appetite
• headache
• fatigue
• insomnia
• dizziness
• drowsiness
• muscle pain

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is best to store it at room temperature between 1°C and 30°C.

Appearance

Yellowish oval film-coated tablet

Package unit

Bottle packaging - 100 tablets/bottle, Bottle packaging - 30 tablets/bottle