Improvement of cognitive function in moderate to severe Alzheimer's disease
Who takes it
Adults
Adult dose
Patients requiring the combination of donepezil hydrochloride 10 mg and memantine hydrochloride 20 mg should take one tablet daily at the same time before bedtime. This medication can be taken regardless of food intake.
Improvement of cognitive function in moderate to severe Alzheimer's disease
Moderate Alzheimer's disease
severe Alzheimer's disease
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The combination therapy of donepezil and memantine is used for the treatment of moderate to severe Alzheimer's disease. Donepezil helps improve cognitive ability by enhancing brain function, while memantine slows down the deterioration of brain function by regulating excessive stimulation of nerve cells. This combination therapy contributes to effectively improving the symptoms of Alzheimer's disease. Therefore, this therapy is used to improve the cognitive function and quality of life of patients with moderate to severe Alzheimer's disease.
How to take
Adult dose
Patients requiring the combination of donepezil hydrochloride 10 mg and memantine hydrochloride 20 mg should take one tablet daily at the same time before bedtime. This medication can be taken regardless of food intake.
Precautions
This medication should not be used in certain patients. For example, individuals allergic to this drug or its components, those with severe liver or kidney dysfunction, pregnant or breastfeeding women, and those with lactose intolerance should not take this medication.
Additionally, patients with epilepsy or a history of seizures should use this medication carefully, as there may be an increased risk of side effects when combined with certain medications. Individuals with heart diseases or hypertension also require special monitoring when taking this medication.
Various adverse reactions may occur during treatment with this medication. Commonly experienced side effects include nausea, vomiting, diarrhea, dizziness, insomnia, headaches, and fatigue, while severe cases may involve heart problems, liver dysfunction, cerebrovascular issues, muscle abnormalities, and difficulty breathing. If these symptoms occur, consult a doctor immediately.
Pregnant or breastfeeding women should avoid taking this medication, and if necessary, should consult with a specialist for careful consideration.
This medication is not recommended for children and adolescents under 18 years of age, as safety and efficacy have not been established.
In cases of overdose, symptoms such as nausea, vomiting, muscle weakness, confusion, and seizures may occur, so immediate medical attention is necessary.
This medication may affect driving or machinery operation, so caution is needed during the initial dosing or when changing the dosage.
Regular monitoring of liver functions, heart conditions, and blood tests may be necessary during treatment, and all medications being taken should be disclosed to the healthcare provider due to potential drug interactions.
Finally, this medication should be kept out of the reach of children and not transferred to other containers for safety reasons.
Not everyone experiences these, and they can vary from person to person.
Storage
This medication should be stored in a sealed container to protect it from air and moisture. It is also recommended to store the medication at room temperature between 1 and 30 degrees Celsius. Proper storage maintains the medication's efficacy and prevents deterioration.
Appearance and packaging
Appearance
Yellow oval film-coated tablet
Package unit
30 tablets/bottle, 100 tablets/bottle
Same-ingredient medicines
Even with the same ingredient, strength, dosage form and how it is taken can differ.
Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
Questions about this medicine
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety. Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.