Medication info
Amloget Tablet 10/5/10 mg (Amlodipine, Rosuvastatin, Ezetimibe)

Amloget Tablet 10/5/10 mg (Amlodipine, Rosuvastatin, Ezetimibe)

Prescription medicationTablet경구
Ingredient · strength
Ezetimibe›10mg / 1 tabletRosuvastatin Calcium›5.2mg / 1 tabletAmlodipine Besylate›13.889mg / 1 tablet
Manufacturer / importer
(주)셀트리온제약
Appearance
Pink, convex, round film-coated tablets on both sides
Packaging
Bottle package - 30 tablets/bottle, Bottle package - 100 tablets/bottle
Approval status
Active

MFDS item code 202402807 · Approved 2024.11.27 · Insurance code 693903920

Summary

Main use
(Hypertension, Angina) Improvement of myocardial ischemia and dyslipidemia
Who takes it
Adults
Adult dose
This medication should be taken once daily at a dose of one tablet with water, regardless of meals. It is advised to take it at the same time each day if possible. Administer 5 mg of amlodipine orally once daily, which can be increased to a maximum of 10 mg daily based on patient response. The ezetimibe/rosuvastatin combination drug is administered once daily, regardless of meals. For primary hypercholesterolemia, an initial dose of 10/5 mg daily is recommended.

Ingredients

Manufacturer
(주)셀트리온제약

Efficacy & effects

(Hypertension, Angina) Improvement of myocardial ischemia and dyslipidemia

  • Hypertension
  • fixed obstruction of coronary artery
  • vascular spasms
  • vascular constriction
  • myocardial ischemia
  • primary hypercholesterolemia
  • elevated total cholesterol
  • LDL cholesterol
  • apo B protein
  • triglycerides
  • non-HDL cholesterol
View approved original text

This medication is used for patients requiring combined administration of amlodipine and ezetimibe/rosuvastatin. Amlodipine helps treat hypertension and myocardial ischemia caused by stable and variant angina. Additionally, it is used to reduce the risk of hospitalization due to angina and the risk related to angioplasty in patients with coronary artery disease who have no heart failure and with an ejection fraction of more than 40%. Ezetimibe and rosuvastatin help control blood cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia, assisting the effects of dietary therapy. This medication is effective in improving both blood pressure and blood lipid levels and is used to enhance cardiovascular health.

How to take

Adult dose

This medication should be taken once daily at a dose of one tablet with water, regardless of meals. It is advised to take it at the same time each day if possible. Administer 5 mg of amlodipine orally once daily, which can be increased to a maximum of 10 mg daily based on patient response. The ezetimibe/rosuvastatin combination drug is administered once daily, regardless of meals. For primary hypercholesterolemia, an initial dose of 10/5 mg daily is recommended.

Precautions

This medication can cause severe problems with muscles, so seek immediate consultation with a doctor if you experience severe muscle pain or muscle weakness symptoms. This medication should not be administered to patients with very poor liver function or active liver disease. Women who are pregnant or may become pregnant, and those who are breastfeeding should not use this medication. Patients with severely impaired kidney function should not use this medication, and patients with slightly impaired kidney function should use it with caution. Since this medication lowers blood pressure, caution should be exercised in patients with hypotension. During treatment with this medication, periodic liver function tests and muscle-related tests should be performed, and any abnormal symptoms should be reported to healthcare personnel immediately. The risk of side effects may increase when this medication is taken with certain other medications, so if you are currently taking any medication, be sure to inform your doctor. Patients who consume alcohol excessively or have a history of liver disease should be particularly cautious when using this medication. Elderly patients are at higher risk for muscle disorders, so close monitoring is necessary when taking this medication. Symptoms such as dizziness may occur while driving or operating machinery, so caution is advised. This medication contains lactose, so patients with lactose intolerance should not take it. In case of overdose, severe hypotension or heart function decline may occur, so it is important to adhere strictly to the dosage. If an overdose occurs, you should visit the hospital immediately. The safety and efficacy of this medication have not been established in children, so it is best not to use it.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in mouth/eye mucosa, severe allergic reaction, severe skin adverse reaction, difficulty breathing or shortness of breath, asthma attacks, respiratory issues with cough+fever, respiratory problems, yellowing of skin or eyes (jaundice), severe lethargy, liver abnormalities (jaundice), sudden and

Mild side effects

  • Chest pain
  • swelling
  • generalized edema
  • headache
  • upper respiratory tract infection
  • back pain
  • shortness of breath
  • acute myocardial infarction
  • abdominal pain
  • insomnia
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  • skin mass
  • congestion
  • flushing
  • fatigue
  • myalgia
  • dizziness
  • drowsiness
  • nausea
  • weakness
  • lethargy
  • pain
  • weight changes
  • hypotension
  • vasculitis
  • tension increase
  • sensory decrease/sensory abnormality
  • peripheral neuropathy
  • syncope
  • taste disturbance
  • tremors
  • extrapyramidal disorders
  • erectile dysfunction
  • gynecomastia
  • change in bowel habits
  • vomit

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air or moisture from entering. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius to preserve the effectiveness and safety of the medication.

Appearance and packaging

Appearance

Pink, convex, round film-coated tablets on both sides

Package unit

Bottle package - 30 tablets/bottle, Bottle package - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.