Amlojet Tablets 10/20/10 mg (Amlodipine, Rosuvastatin, Ezetimibe)

Adult dose

This medication is taken as one tablet once a day with water, regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning) when possible. Amlodipine is administered orally at a dose of 5 mg once daily and can be increased to a maximum of 10 mg per day based on the patient's response. The Ezetimibe/Rosuvastatin combination should be taken once a day regardless of meals. For primary hypercholesterolemia, the dosage range is 10/

This medication may rarely cause rhabdomyolysis due to the Rosuvastatin component, leading to a risk of acute renal failure. Therefore, patients exhibiting serious myopathy symptoms or those with risk factors such as severe infections, hypotension, major surgery, trauma, endocrine and electrolyte disorders, or uncontrolled seizures should temporarily discontinue or stop using this medication. Patients with allergies to this medication's ingredients or similar medications, pregnant or potentially pregnant women, nursing mothers, patients with severe liver dysfunction, active liver disease, severe aortic stenosis, muscle disorder patients, those taking cyclosporine, and patients with severe kidney impairment should not use this medication. Patients at high risk for myopathy or rhabdomyolysis, such as those with moderate to severe kidney impairment, hypothyroidism, a history of genetic muscle disease, a history of muscle toxicity due to statins or fibrates, alcohol dependence, and patients of Asian descent should use this medication with caution, and muscle-related tests should be conducted as necessary. This medication can affect liver function, thus regular liver function tests should be performed before and during treatment, and if liver damage symptoms appear, use should be immediately discontinued. Symptoms such as muscle pain, muscle cramping, or muscle weakness may occur; if these symptoms develop, consult a physician immediately. This medication should not be used during pregnancy or breastfeeding, and women of childbearing potential should use appropriate contraception. Elderly patients or those with kidney impairment should be monitored closely due to a higher risk of myopathy. This medication may interact with several other medications; therefore, if taking other medications, it is essential to inform the doctor or pharmacist, particularly when used in conjunction with fibrates, cyclosporine, warfarin, certain antibiotics, etc. In case of overdose, symptoms such as low blood pressure or decreased cardiac function may occur; immediate medical attention should be sought.

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing → severe allergic reaction. Severe skin reaction with high fever and rash, blisters, peeling skin, pain in mucous membranes of mouth/eyes → severe skin abnormal reaction. Shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough + fever → respiratory problems. Yellowing of skin or eyes (jaundice), extreme fatigue → liver problems (jaundice). Sudden and very severe headache,

Mild side effects

• Headache
• dizziness
• drowsiness
• fatigue
• swelling
• abdominal pain
• nausea
• diarrhea
• myalgia
• malaise

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. Additionally, it is best to store the medicine at room temperature between 1 to 30 degrees Celsius. Storing it this way will help maintain the medication's effectiveness for a longer time.

Appearance

Pink, biconvex, round film-coated tablets

Package unit

Bottle packaged - 30 tablets/bottle, Bottle packaged - 100 tablets/bottle