Niron Tablet 10 mg (Nisergoline)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. For patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This drug should not be used in certain patients. For example, individuals allergic to this medication or ergot alkaloids should not take it. Patients with acute myocardial infarction or acute bleeding should also refrain from taking this drug. Patients taking sympathomimetics, those with very low heart rates, those with incomplete hemostasis following intracranial hemorrhage, and those with orthostatic hypotension should avoid this drug. Patients with mild bradycardia or impaired renal function should take this drug cautiously. Gastrointestinal side effects, such as appetite loss, diarrhea, constipation, nausea, and vomiting, may occur rarely when using this drug. Liver enzyme levels may rise due to abnormal liver function. Cardiovascular adverse reactions such as dizziness, orthostatic hypotension, hypertension, and hypotension can also appear rarely. Neurological symptoms may include drowsiness, headache, fatigue, insomnia, and, rarely, hypersensitivity reactions such as skin rashes or itching have been reported. Taking this medication with other antihypertensive agents may cause blood pressure to drop too low, so blood pressure should be checked frequently. Additionally, since it can affect uric acid metabolism, patients with a history of hyperuricemia or gout should be cautious. Caution is necessary after taking this drug when driving or operating machinery. This drug is metabolized by certain enzymes in the liver, so interactions with other medications utilizing the same enzyme pathway may occur. Pregnant women or those who may become pregnant should carefully consider the risks and benefits of using this drug, and breastfeeding mothers should either avoid administering it or discontinue breastfeeding. Elderly patients may require careful dosage adjustments due to potential decreases in bodily functions. Safety in children has not been established, and usage is not recommended. In case of overdose, blood pressure may temporarily drop, so blood pressure changes should be monitored closely and appropriate measures should be taken. This drug should be stored out of reach of children and kept securely in its original container. Transferring it to another container may lead to misuse or loss of quality.

• Loss of appetite
• diarrhea
• constipation
• nausea
• vomiting
• intermittent upper abdominal pain
• cramping
• thirst
• elevation of ALT
• elevation of AST

This drug should be stored in a tightly sealed container that does not allow light, at room temperature between 1 degree and 30 degrees Celsius. Proper storage can maintain the drug's effectiveness and prevent degradation.

Appearance

White, round, film-coated tablet

Package unit

30 tablets/bottle, 60 tablets/bottle