Medication info

Merabutin Tablets (Trimebutine Maleate)

OTC medicationTablet경구
Ingredient · strength
Trimebutine Maleate›Strength being verified
Manufacturer / importer
한솔신약(주)
Appearance
White round tablet
Packaging
PTP - 10 tablets/box [10 tablets/PTP*1], PTP - 20 tablets/box [10 tablets/PTP*2], PTP - 100 tablets/box [10 tablets/PTP*10], PTP - 240 tablets/box [(10 tablets/PTP*12)*2], Bottle - 100 tablets/bottle, Bottle - 500 tablets/bottle, Bottle - 1000 tablets/bottle
Approval status
Active

MFDS item code 202402193 · Notified 2024.09.09

Summary

Main use
Improvement of acid reflux and gastrointestinal disorders (abdominal pain, dyspepsia), relief of irritable bowel syndrome, treatment of pediatric vomiting and gastrointestinal obstruction
Who takes it
Adults
Adult dose
Adults: Administer 100-200 mg of Trimebutine Maleate orally 3 times a day before meals. Adjust dosage appropriately based on age and symptoms.

Ingredients

Manufacturer
한솔신약(주)

Efficacy & effects

Improvement of acid reflux and gastrointestinal disorders (abdominal pain, dyspepsia), relief of irritable bowel syndrome, treatment of pediatric vomiting and gastrointestinal obstruction

  • Acid reflux
  • hiatal hernia
  • gastric and duodenal inflammation
  • gastric and duodenal ulcers
  • abnormal digestive function
  • abdominal pain
  • dyspepsia
  • nausea
  • vomiting
  • irritable bowel syndrome
  • spastic colon
  • habitual vomiting
View approved original text

This medication helps alleviate abnormal digestive symptoms caused by esophageal reflux and hiatal hernia, such as abdominal pain, dyspepsia, nausea, and vomiting. It also improves discomfort caused by gastric and duodenal inflammation and ulcers. It is effective in alleviating abdominal pain and discomfort from irritable bowel syndrome and spastic colon. In children, it is used to relieve symptoms of habitual vomiting and non-infectious gastrointestinal passage issues, such as constipation or diarrhea. Overall, it aids in treating gastrointestinal dysfunction, thereby improving the quality of life for patients.

How to take

Adult dose

Adults: Administer 100-200 mg of Trimebutine Maleate orally 3 times a day before meals. Adjust dosage appropriately based on age and symptoms.

Precautions

This medication may affect the gastrointestinal system and can rarely cause symptoms such as constipation or diarrhea, audible gas in the intestines, nausea, vomiting, dyspepsia, dry mouth, or a feeling of numbness in the mouth. Additionally, cardiovascular symptoms such as palpitations may occur rarely. It can also impact the nervous system, leading to fatigue, drowsiness, dizziness, lethargy, and headaches, which are rare side effects. There are rare reports of elevated liver enzyme levels, indicating potential liver function impact. Rash or other hypersensitivity reactions may occur, although infrequently, and if such symptoms appear, the use of this medication should be discontinued. The safety of this medication during pregnancy is not well established, so women who are pregnant or may become pregnant should use it only if the benefits outweigh the risks. Safety during breastfeeding has also not been confirmed, so it is advisable to avoid it whenever possible, and if necessary, to discontinue breastfeeding.

Side effects and when to seek care immediately

Mild side effects

  • Constipation
  • diarrhea
  • abdominal bloating
  • nausea
  • vomiting
  • dyspepsia
  • dry mouth
  • feeling of oral numbness
  • palpitations
  • fatigue
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  • drowsiness
  • dizziness
  • lethargy
  • headaches
  • rash

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius (room temperature). Proper storage helps retain the medication's efficacy for an extended period.

Appearance and packaging

Appearance

White round tablet

Package unit

PTP - 10 tablets/box [10 tablets/PTP*1], PTP - 20 tablets/box [10 tablets/PTP*2], PTP - 100 tablets/box [10 tablets/PTP*10], PTP - 240 tablets/box [(10 tablets/PTP*12)*2], Bottle - 100 tablets/bottle, Bottle - 500 tablets/bottle, Bottle - 1000 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.