Trinam 5/1000 mg Extended-Release Tablet (Linagliptin, Metformin)

Adult dose

The dosage of this medication is determined within the limits of the maximum recommended daily doses for each ingredient: Linagliptin 5 mg (Linagliptin benzoate 6.67 mg) and extended-release Metformin hydrochloride 2000 mg. It is taken once daily with the evening meal. For the 5/1000 mg extended-release tablet, take 1 tablet once daily. For the 2.5/1000 mg extended-release tablet, take 2 tablets once daily.

This drug is used for the treatment of diabetes and helps lower blood sugar. However, it may rarely cause a serious condition called lactic acidosis, warranting caution. It should not be used in patients with poor kidney function, liver dysfunction, or in acute conditions such as acute myocardial infarction or severe infections. Patients with allergies to any component of this drug or those with type 1 diabetes should also avoid its use. There is a risk of hypoglycemia, so blood glucose changes must be carefully monitored when used with insulin or sulfonylureas. In situations where renal function is impaired, temporary discontinuation of this drug may be necessary. Additionally, acute pancreatitis or blistering skin conditions may develop, so consult a physician immediately if symptoms occur. This drug may lower vitamin B12 levels, necessitating regular blood tests during prolonged use. Alcohol consumption can increase the risk of lactic acidosis and should be avoided. Use during pregnancy or breastfeeding should be avoided, and patients planning pregnancy should consult a physician. Elderly patients have a higher risk of kidney function deterioration and require dosage adjustments and regular kidney function tests. In situations that could impact kidney function, such as surgery or radiological examinations, administration of this drug should be temporarily suspended. This medication must be swallowed whole and should not be chewed or crushed. Be aware that there may be drug interactions, so inform your physician or pharmacist of any other medications you are taking. Overdose may cause gastrointestinal disorders or lactic acidosis, requiring immediate medical attention. Store this medication away from children's reach, keep it in a dry place, and store it in the original container.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, lactic acidosis, pancreatitis, bullous pemphigoid, abnormal liver function (including hepatitis and jaundice), acute myocardial infarction, angina, cardiac arrest, acute kidney injury, kidney transplant failure, severe allergic reactions, severe skin reactions, serious neurological symptoms (severe headache, seizures, confusion, visual disturbances, paralysis), severe edema or urination abnormalities (decreased urine output, systemic severe

Mild side effects

• Pharyngitis
• taste disturbance
• cough
• loss of appetite
• diarrhea
• constipation
• nausea
• vomiting
• abdominal pain
• oral ulcer

This drug is sensitive to air and moisture; therefore, it should be stored in a sealed container. It is crucial to maintain a storage temperature between 1 and 30 degrees Celsius. This helps ensure the drug's effectiveness is safely preserved for an extended period.

Appearance

This drug is a yellow oval-shaped extended-release film-coated tablet.

Package unit

30 tablets/bottle, 60 tablets/bottle