Medication info
Sarin Tablet 10 mg (Nisergoline)

Sarin Tablet 10 mg (Nisergoline)

Prescription medicationTabletOral
Ingredient · strength
Nicergoline›10mg / 1 tablet
Manufacturer / importer
Hana Pharmaceutical Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202401524 · Approved 2024.06.24 · Insurance code 657808220

Summary

Main use
Improvement of decreased motivation and dementia syndrome, relief of atherosclerotic headaches in older adults, adjunctive treatment of hypertension
Who takes it
Adults
Adult dose
* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally per dose, 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. Reduce the dose in patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL).

Ingredients

Manufacturer
Hana Pharmaceutical Co., Ltd.

Efficacy & effects

Improvement of decreased motivation and dementia syndrome, relief of atherosclerotic headaches in older adults, adjunctive treatment of hypertension

  • Chronic cerebrovascular disorder
  • decreased motivation
  • atherosclerotic headache in the elderly
  • memory impairment
  • concentration disorders
  • judgment impairment
  • lack of initiative
View approved original text

This medication is used to improve decreased motivation caused by chronic cerebrovascular disorders after cerebral infarction. It also helps as an adjunct treatment for elderly patients with atherosclerotic headaches and hypertension. Furthermore, the 30 mg formulation is effective in treating symptoms such as memory impairment, concentration disorders, decreased judgment, and lack of initiative in patients with primary degenerative vascular dementia and mixed dementia. This drug is used to improve neurological function and alleviate dementia symptoms.

How to take

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally per dose, 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. Reduce the dose in patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL).

Precautions

This medication should not be used in certain patients. People who are allergic to this medication or ergot alkaloids should not take it. Patients with acute problems related to the heart or acute bleeding should also avoid this medication. Patients taking sympathetic nerve-stimulating drugs should also avoid this medication. Patients with very slow heart rates or those who have not had hemostasis after a cerebral hemorrhage should not use this medicine. Patients with orthostatic hypotension should also be cautious. Patients with mild bradycardia or decreased kidney function should use this medication with caution. This medication can rarely cause symptoms such as indigestion, diarrhea, constipation, nausea, vomiting, abdominal pain, or dry mouth. Liver function abnormalities may lead to elevated liver enzyme levels. Symptoms such as dizziness, orthostatic hypotension, blood pressure changes, headaches, drowsiness, fatigue, insomnia, and skin rashes may occur. Allergic reactions such as rashes, itching, and flushing may occur, so caution is advised. When taken with other medications that lower blood pressure, there is a risk of blood pressure dropping too low, so blood pressure should be monitored frequently. This medication may affect uric acid levels, so patients with a history of gout should use it carefully. After taking this medication, be cautious when driving or operating machinery. This medication is metabolized by specific enzymes in the liver, which may cause interactions with other medications. Women who are pregnant or may become pregnant should carefully consider the risks and benefits of taking this medication. Breastfeeding women should avoid taking this medication if possible or stop breastfeeding, as this medication may transfer into breast milk. Older patients may have decreased bodily function, so caution such as dose reduction is necessary. It is advisable not to use this medication in children as its safety has not been confirmed. In case of overdose, blood pressure may decrease, so blood pressure status should be monitored closely, and necessary actions should be taken. This medication should be kept out of reach of children and stored in its original container, sealed.

Side effects

Loss of appetite, diarrhea, constipation, nausea, vomiting, intermittent upper abdominal pain or cramps, thirst, elevated ALT, elevated AST, dizziness, orthostatic dysregulation, hypertension, elevated blood uric acid, hypotension, drowsiness, malaise, headache, tinnitus, fatigue, insomnia, rash, urticaria, pruritus, flushing, heat sensation, nightmares, mood disturbances, dyspepsia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. The recommended storage temperature is between 1 degree and 30 degrees Celsius at room temperature. Proper storage will help maintain the medication's effectiveness.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.