Medication info
Jeniser Tablet 10 mg (Nisergoline)

Jeniser Tablet 10 mg (Nisergoline)

Prescription medicationTabletOral
Ingredient · strength
Nicergoline›10mg / 1 tablet
Manufacturer / importer
Albozen Korea Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202401523 · Approved 2024.06.24 · Insurance code 652607350

Summary

Main use
Improvement of symptoms of cerebrovascular disorders and dementia, relief of atherosclerotic headaches, adjunctive treatment of hypertension
Who takes it
Adults
Adult dose
* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally per dose, 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. Reduce the dose in patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL).

Ingredients

Manufacturer
Albozen Korea Co., Ltd.

Efficacy & effects

Improvement of symptoms of cerebrovascular disorders and dementia, relief of atherosclerotic headaches, adjunctive treatment of hypertension

  • Decreased motivation due to chronic cerebral circulation disorder
  • arteriosclerotic headache in the elderly
  • memory impairment
  • concentration difficulties
  • judgment impairment
  • lack of initiative
View approved original text

This medication can be helpful when there is a decrease in motivation due to chronic cerebral circulation disorder caused by aftereffects of cerebral infarction. Additionally, it is used to alleviate arteriosclerotic headache appearing in the elderly, and acts as an adjunctive therapy for hypertension. The 30 mg dosage is effective for treating major symptoms of primary degenerative vascular dementia and complex dementia, such as memory impairment, concentration difficulties, judgment impairment, and lack of initiative. Overall, it is a medication that helps improve cerebrovascular-related symptoms and treat dementia.

How to take

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally per dose, 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. Reduce the dose in patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL).

Precautions

This medication should not be used in certain patients. For example, it should not be administered to patients allergic to this medication or ergot alkaloids, those with acute myocardial infarction or acute bleeding, patients taking sympathomimetics, patients with significantly low heart rates, patients who have not achieved hemostasis after intracranial hemorrhage, and those with orthostatic dysregulation. Caution should be exercised when using this medication in patients with mild bradycardia or impaired renal function. During treatment, rare gastrointestinal symptoms such as anorexia, diarrhea, constipation, nausea, and vomiting may occur, and liver function test values may rise. Moreover, neurological symptoms such as dizziness, blood pressure changes, drowsiness, headaches, and insomnia may occur rarely. Allergic reactions such as rash, hives, itching, and flushing may occur, and if any abnormal symptoms arise, immediate consultation with a physician is necessary. Blood pressure may lower excessively if this medication is used with other antihypertensive agents, so frequent blood pressure monitoring is recommended. It may also affect uric acid metabolism, requiring caution in patients with a history of gout. Drowsiness may occur when driving or operating machinery, so caution is needed. This medication is metabolized in the liver by specific enzymes, thus potential interactions with other medications may occur, and you should inform your healthcare provider about any medications you are taking. Women who are pregnant or may become pregnant should carefully weigh the benefits and risks before taking this medication, and it is recommended to avoid use while breastfeeding or to stop breastfeeding if it must be used. Elderly patients may require dose adjustment due to potential declines in bodily functions. The safety of use in children has not been sufficiently confirmed, so caution is necessary in pediatric use. In cases of overdose, blood pressure may temporarily drop, thus blood pressure should be monitored, and appropriate actions should be taken. Finally, this medication should be stored out of reach of children, and stored in its original container to prevent misuse or degradation of quality.

Side effects

  • Loss of appetite
  • diarrhea
  • constipation
  • nausea
  • vomiting
  • recurrent upper abdominal pain or cramps
  • thirst
  • increased ALT
  • increased AST
  • dizziness
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  • orthostatic hypotension
  • hypertension
  • increased blood uric acid
  • blood pressure drop
  • drowsiness
  • fatigue
  • headache
  • tinnitus
  • tiredness
  • insomnia
  • rash
  • urticaria
  • itching
  • flushing
  • warmth
  • nightmares
  • mood disturbances
  • dyspepsia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. This helps to maintain the effectiveness and safety of the medication.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.