Olmesartan Medoxomil / Hydrochlorothiazide / Amlodipine Besylate Hydrate Tablets 2.5/40/12.5 mg

Adult dose

This medication should be taken once daily with water, regardless of meals. It is advised to take it at the same time every day (for example, in the morning). The maximum dose is Olmesartan/Amlodipine/Hydrochlorothiazide of 5/40/25 mg. The maximum blood pressure-lowering effect appears within 2 weeks after administration, so dosage adjustments should be made considering the patient's blood pressure response at intervals of more than 2 weeks. The recommended doses are:

Child dose

Safety and efficacy in pediatric patients under 18 years of age have not been established, therefore administration of this medication is not recommended.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, therefore it should be discontinued immediately if pregnancy is confirmed. It is safer not to use this medication if there is an allergy or hypersensitivity to any of the ingredients or similar medications. Patients with severe hypotension, severe heart valve disease, unstable heart failure after acute myocardial infarction, or severe renal or liver dysfunction should avoid taking this medication. In cases of reduced salt or blood volume, blood pressure may drop excessively in the early stages of taking this medication; thus, monitoring the condition before and during treatment is essential. Patients with renal impairment or those who have received a kidney transplant should have regular tests of kidney function and blood electrolyte levels while taking this medication. Patients with severely impaired liver function or specific heart diseases also need to use this medication with caution. This medication has a blood pressure-lowering effect; therefore, dizziness or drowsiness may occur during activities requiring careful attention, such as operating machinery or driving. Regular blood tests to check electrolytes and renal function are essential while taking this medication. Patients with diabetes or gout should closely manage changes in blood sugar and uric acid levels while taking this medication. In photosensitivity reactions may occur, care should be taken to avoid excessive exposure to sunlight or ultraviolet rays, and if any abnormal symptoms appear, immediate consultation with a physician is advised. This medication is not recommended for breastfeeding women, and consultation with a physician is required if breastfeeding persists, as it may affect the baby. Safety and efficacy have not been established for patients under 18 years of age, and its use should be avoided. Seniors may have decreased kidney and liver function, so they should adjust the dosage and be attentive to side effects while taking it. In the case of overdose, symptoms such as hypotension, palpitations, and bradycardia may occur, and immediate medical attention is necessary.

Serious side effects

hives, severe swelling (edema), difficulty breathing, jaundice, sudden and severe headache, seizures, confusion, paralysis, significantly reduced urine output, severe swelling overall accompanied by increased blood pressure, anaphylactic reaction, myocardial infarction, acute renal failure, pulmonary edema, angioedema, vasculitis, thrombosis, embolism, acute respiratory distress syndrome (ARDS), Stevens-Johnson syndrome, Quincke's edema, acute interstitial pneumonia, jaundice (hepatic)

Mild side effects

• peripheral edema
• headache
• dizziness
• upper respiratory infection
• nasopharyngitis
• urinary tract infection
• sialadenitis
• leukopenia
• thrombocytopenia
• bone marrow suppression

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is best kept at room temperature between 1 to 30 degrees Celsius.

Appearance

light yellow round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle