Medication info
OneTwoJeng 15/50 mg (Clomipramine Hydrochloride, Sildenafil Citrate)

OneTwoJeng 15/50 mg (Clomipramine Hydrochloride, Sildenafil Citrate)

Prescription medicationTablet
Ingredient · strength
Clomipramine Hydrochloride›15mg / 1 tabletSildenafil Citrate›70.23mg / 1 tablet
Manufacturer / importer
(주)씨티씨바이오
Appearance
Pink rectangular film-coated tablet
Packaging
5 tablets/box [5 tablets × 1 PTP], 10 tablets/box [5 tablets × 2 PTP]
Approval status
Active

MFDS item code 202401189 · Approved 2024.05.16

Summary

Main use
Treatment of premature ejaculation
Who uses it
Adults
Adult dosage
Adult males take 1 tablet of this medication about 2 to 4 hours before sexual activity. The maximum number of doses should not exceed 1 within 24 hours.

Ingredients

Manufacturer
(주)씨티씨바이오

Efficacy & effects

Treatment of premature ejaculation

  • Premature ejaculation
View approved original text

Clomipramine is used when premature ejaculation is not well controlled by monotherapy. This medication helps manage symptoms more effectively based on the situation. In other words, it is utilized when additional control is needed for the treatment of premature ejaculation. Patients can expect treatment benefits when taking this medication as directed by their physician.

Dosage and Administration

Adult dosage

Adult males take 1 tablet of this medication about 2 to 4 hours before sexual activity. The maximum number of doses should not exceed 1 within 24 hours.

Precautions

This medication is primarily used for the treatment of premature ejaculation and contains ingredients used as antidepressants, but it should not be used in patients with depression or psychiatric disorders. This medication should not be used in children and women, and symptoms of depression must be checked carefully before taking the medication. Taking it together with other antidepressants is prohibited, and it should not be administered to patients with psychiatric disorders or accompanied by depression. Taking this medication with nitrate compounds or NO donors that lower blood pressure may cause excessive drops in blood pressure, and it must be discussed with a physician. Patients with cardiovascular disease should thoroughly check their heart condition before taking this medication and should not use it in situations that can strain the heart. This medication can temporarily lower blood pressure by dilating blood vessels, so special caution is needed for patients with orthostatic hypotension or cardiovascular disease. Patients with severe arrhythmia, heart failure, unstable angina, severe liver or kidney disease, glaucoma, or pigmentary retinopathy should not use this medication. If erection lasts more than 4 hours, immediate medical attention is required, as untreated conditions may lead to permanent damage. This medication has many interactions with specific drugs, so if you are currently taking any medications, be sure to inform your doctor. Women who are pregnant or breastfeeding should not use this medication, and it is also not administered to the elderly or children. In case of overdose, serious heart and neurological abnormalities may occur, and immediate medical treatment is needed. Dizziness, drowsiness, visual disturbances may occur during treatment, necessitating caution when driving or operating machinery, and it is advised to avoid mixing with alcohol or other central nervous system depressants. This medication does not prevent sexually transmitted diseases during intercourse, so separate preventive measures should be taken. This medication is specifically aimed at men with premature ejaculation, and careful observation should be maintained before and after taking as per the physician's instructions. When storing, keep it out of the reach of children and do not transfer to other containers.

Side effects and when to seek care immediately

Serious side effects

Death due to cardiovascular adverse reactions, priapism (erection lasting more than 4 hours with pain), sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, shortness of breath or difficulty breathing, asthma attacks, breathing abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, significant reduction in urine output, severe swelling throughout the body and blood pressure

Mild side effects

  • Headache
  • nausea
  • flushing
  • dizziness
  • palpitations
  • drowsiness
  • burning sensation
  • dyspepsia
  • diarrhea
  • facial flushing
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  • heat sensation
  • nasal congestion
  • conjunctival injection
  • increased AST
  • tension headache
  • lethargy
  • memory impairment
  • confusion
  • tremors
  • abdominal pain
  • gastrointestinal upset
  • dry mouth
  • vomiting
  • abdominal discomfort
  • toothache
  • weakness
  • sweating
  • chest pain
  • chest discomfort
  • facial pain
  • abnormal sensations
  • cough
  • lung tumor
  • congestion
  • yawning
  • runny nose
  • eyelid dysfunction

Not everyone experiences these, and they can vary from person to person.

Storage

This medication can be sensitive to air or moisture, so it must be stored in a tightly sealed container. The storage temperature should be maintained between 1 degree and 30 degrees Celsius at room temperature. This will help keep the medication effective and safe for a long time.

Appearance and packaging

Appearance

Pink rectangular film-coated tablet

Package unit

5 tablets/box [5 tablets × 1 PTP], 10 tablets/box [5 tablets × 2 PTP]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.