Amantine Tablet 20mg (Memantine Hydrochloride)

Adult dose

This medication is taken orally once daily, and it should be administered at the same time each day. If necessary, it can be prescribed as a twice-daily dosage. Dosage Increase: The maximum daily dose is 20mg, and it should be increased by 5mg per week over the first 3 weeks. - First week (Days 1-7): 5mg once daily - Second week (Days 8-14): 10mg once daily - Third week (Days 15-21): 15mg once daily

This medication should not be used in patients with hypersensitivity to its components or in patients with severe liver or kidney impairments. It should be used cautiously in patients with epilepsy or a history of seizures, as well as in patients with a predisposition to seizures. Using NMDA antagonists such as amantadine, ketamine, or dextromethorphan together may increase central nervous system side effects, so they should not be combined. Careful monitoring is advised in situations where urine pH may increase, for example, due to dietary changes or certain urinary tract infections. Caution is warranted in patients with recent myocardial infarction, congestive heart failure, or uncontrolled hypertension, as the safety of this drug has not been sufficiently established in these populations. During the use of this medication, side effects such as dizziness, headache, constipation, drowsiness, and hypertension may occur; if symptoms are severe, consultation with a healthcare professional is advised. This medication may interact with other drugs, so special caution is needed when taken with levodopa, dopamine agonists, anticholinergics, barbiturates, antipsychotics, or skeletal muscle relaxants. Women who are pregnant or may become pregnant should consult their physician before taking this medication, and nursing mothers are recommended to stop breastfeeding while taking this medication. It is advisable to avoid using this medication in children or adolescents under 18 years of age, as its safety and efficacy have not been established. In cases of overdose, symptoms such as confusion, drowsiness, dizziness, hallucinations, seizures, and vomiting may occur, so immediate medical attention is required. This medication can affect the central nervous system, so caution is necessary when driving or operating machinery. Store out of reach of children and do not transfer the medication to other containers to ensure safety and maintain quality.

Serious side effects

• Seizures
• heart failure
• venous thrombosis/thromboembolism
• shortness of breath
• pancreatitis
• hepatitis
• hallucinations
• psychotic reactions

Mild side effects

• Dizziness
• headache
• constipation
• drowsiness
• hypertension
• fungal infection
• drug hypersensitivity reaction
• confusion
• hallucinations
• psychotic reactions

This medication should be stored in a tightly closed container to protect it from air and moisture, ideally at room temperature between 1 and 30 degrees Celsius. Storing it this way can help maintain the medication's effectiveness over time.

Appearance

Pink, oval, film-coated tablet

Package unit

Bottle packaging - 30 tablets/bottle [Bottle: HDPE, Cap: LDPE], Bottle packaging - 100 tablets/bottle [Bottle: HDPE, Cap: LDPE]