Medication info
Zaquborjeong 20 mg (Zastaprazan Citrate)

Zaquborjeong 20 mg (Zastaprazan Citrate)

Prescription medicationTabletOral
Ingredient · strength
Zastaprazan Citrate›20mg / 1 tablet
Manufacturer / importer
Oncologic Therapeutics Co., Ltd.
Appearance
Pink round film-coated tablet
Packaging
28 tablets/bottle, 7 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 202400960 · Approved 2024.04.24 · Insurance code 078600010

Summary

Main use
Treatment of erosive gastroesophageal reflux disease and gastric ulcers
Who takes it
Adults
Adult dose
This medicine is administered to adults as follows. It may be taken with or without food. 1. Treatment of erosive gastroesophageal reflux disease - Administer 20 mg orally once daily for 4 weeks. If the condition is not resolved, continue treatment for an additional 4 weeks. 2. Treatment of gastric ulcers - Administer 20 mg orally once daily for up to 8 weeks.

Ingredients

Manufacturer
Oncologic Therapeutics Co., Ltd.

Efficacy & effects

Treatment of erosive gastroesophageal reflux disease and gastric ulcers

  • Erosive gastroesophageal reflux disease
  • gastric ulcer
View approved original text

This medication is used to treat erosive gastroesophageal reflux disease and gastric ulcers. Erosive gastroesophageal reflux disease helps alleviate the inflammation caused by gastric acid refluxing into the esophagus, while gastric ulcers assist in healing damage to the stomach lining. Therefore, this medication is effective in improving symptoms of gastrointestinal disorders and promoting recovery.

How to take

Adult dose

This medicine is administered to adults as follows. It may be taken with or without food. 1. Treatment of erosive gastroesophageal reflux disease - Administer 20 mg orally once daily for 4 weeks. If the condition is not resolved, continue treatment for an additional 4 weeks. 2. Treatment of gastric ulcers - Administer 20 mg orally once daily for up to 8 weeks.

Precautions

This medication should not be administered to certain patients. Patients who have had allergic reactions to this medication or its components, as well as those taking medications containing atazanavir, nelpfinavir, or rilpivirine, should not use this medication. Pregnant or breastfeeding women should also not take this medication. Additionally, this medication contains lactose, so patients with genetic issues like lactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should not take it. Patients with impaired liver or kidney function should use this medication with caution, and seniors also need to be careful. Various side effects can occur while taking this medication, including gastrointestinal disturbances, neurological abnormalities, skin rashes, musculoskeletal pain, so any unusual symptoms should be discussed with healthcare providers immediately. This medication suppresses gastric acid, which may increase the risk of bacterial infections due to reduced acidity in the stomach. Particularly in hospitalized patients, caution should be exercised to prevent Clostridium difficile infection, and if diarrhea persists, healthcare providers should be informed. Long-term use may increase the risk of osteoporosis-related fractures, so regular bone density checks and preventative measures should be considered if necessary. Moreover, long-term use for more than three months may lead to hypomagnesemia, necessitating periodic checks of magnesium levels and supplementation when needed. Long-term use of this medication may result in vitamin B12 deficiency, so appropriate testing should be conducted if related symptoms arise. The effects of this medication on driving or operating machinery are unclear, but caution is warranted depending on the patient’s condition. This medication may interact with other drugs, so it's essential to inform healthcare providers about other medications being taken, especially when combined with certain antiviral or antibiotic drugs. Pregnant or breastfeeding women should not use this medication and should discontinue breastfeeding if taking it. The safety and efficacy in children and adolescents have not been adequately confirmed, so use should be avoided. There have been no reported special poisoning symptoms due to overdose, but observation of symptoms and general treatment should be sought if needed. This medication should be kept out of reach of children and it is safer and better for quality maintenance not to transfer it to another container.

Side effects

  • hernia
  • dyspepsia
  • chronic gastritis
  • erosive gastritis
  • nausea
  • abdominal bloating
  • diarrhea
  • duodenal polyps
  • discomfort in the upper abdomen
  • bloating
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  • food poisoning
  • gastric polyps
  • gastritis
  • hemorrhoids
  • intestinal malformation
  • esophageal dysplasia
  • oral dysesthesia
  • vomiting
  • duodenitis
  • constipation
  • hypergastrinemia
  • COVID-19
  • shingles
  • bronchitis
  • miliary cyst
  • headache
  • radiculopathy
  • tension headache
  • tremor
  • migraine
  • drowsiness
  • arthralgia
  • intravertebral disc disorder
  • muscle spasm
  • limb pain
  • increased alanine aminotransferase
  • increased post-void residual
  • weight gain
  • increased blood gastrin
  • hypertriglyceridemia
  • hyperkalemia
  • hyperlipidemia
  • rash
  • pruritus
  • asthenia
  • pain
  • conjunctival deposits
  • dry eye syndrome
  • ligament sprain
  • bruising
  • skin laceration
  • sleep disorder
  • thyroid nodule
  • atrial fibrillation
  • thrombophlebitis
  • hematuria
  • renal cyst
  • dysmenorrhea
  • upper abdominal pain
  • gastroesophageal reflux disease
  • nausea
  • colorectal polyps
  • abdominal discomfort
  • gingival swelling
  • belching
  • passage of bloody stools
  • abdominal pain
  • green nail syndrome
  • nasopharyngitis
  • influenza
  • pulmonary tuberculosis
  • dizziness
  • lumbosacral radiculopathy
  • osteoarthritis
  • back pain
  • chest pain
  • allergic conjunctivitis
  • keratitis
  • fibula fracture
  • hyperplastic gallbladder disease
  • hypertensive heart disease
  • hypertension
  • overactive bladder
  • cough
  • vocal cord hypertrophy

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air and moisture, ideally at room temperature between 1°C and 30°C.

Appearance and packaging

Appearance

Pink round film-coated tablet

Package unit

28 tablets/bottle, 7 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.