Daparin Tablet (Dapagliflozin Propanediol Hydrate, Linagliptin)

Adult dosage

The recommended dosage for patients receiving 10 mg of dapagliflozin and 5 mg of linagliptin is 1 tablet once daily, regardless of meals.

This medication should not be used in certain patients. For instance, it is contraindicated in patients with allergies to the active ingredient or excipients, patients with type 1 diabetes, patients undergoing dialysis, and patients with a history of myocardial infarction. Careful use is required in patients with fluid volume reduction or renal dysfunction. This medication can cause hypotension or sudden changes in renal function, so fluid status and renal function should be checked before administration and monitored continuously after. When used with drugs that may induce hypoglycemia, dosage adjustment of insulin or insulin secretagogues may be necessary to reduce the risk of hypoglycemia. Experience is limited in patients with heart failure, especially those with severe heart failure, so it should be used cautiously. Side effects such as pancreatitis or blistering skin conditions may occur, so any related symptoms should be reported to a physician immediately. This medication may cause side effects such as genital infections, urinary tract infections, fluid volume reduction, hypotension, and diabetic ketoacidosis; therefore, if any abnormal symptoms occur, it is important to inform medical personnel promptly and receive appropriate treatment. It is recommended that women who are pregnant or breastfeeding do not use this medication, and the safety and efficacy in children have not been sufficiently established. For the elderly, special attention should be paid to renal function and fluid status, and there may be drug interactions, so inform medical personnel of any other medications being taken. In case of overdose, contact a medical institution immediately for appropriate treatment.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden severe headache, thunderclap headache, seizures, consciousness confusion, vision abnormalities, paralysis, urination changes

Mild side effects

• Constipation
• diarrhea
• dizziness
• palpitations
• weight loss
• pruritus of the external genitalia
• sweating
• cystitis
• urinary tract infections
• thirst

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, and it is recommended to store it at room temperature between 1°C and 30°C. Storing it this way helps maintain the efficacy of the medication and allows for safe use.

Appearance

Yellow round film-coated tablet

Package unit

28 tablets/box [7 tablets/PTP × 4], 30 tablets/bottle