Medication info
L-O-Gongjeong 10/5 mg (Ezetimibe, Atorvastatin)

L-O-Gongjeong 10/5 mg (Ezetimibe, Atorvastatin)

Prescription medicationTablet
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›5.4225mg / 1 tablet
Manufacturer / importer
(주)보령
Appearance
White oblong film-coated tablet
Packaging
30 tablets/bottle - 30 tablets/bottle
Approval status
Active

MFDS item code 202400664 · Approved 2024.03.26 · Insurance code 641908380

Summary

Main use
Improvement of hypercholesterolemia (primary, mixed) and treatment of dyslipidemia
Who uses it
Adults
Adult dosage
This medication is administered once daily regardless of meals. It is prescribed within a range of 10/5mg to 10/80mg daily. An initial dose of 10/5mg, 10/10mg, or 10/20mg daily is recommended. For patients requiring LDL cholesterol reduction of more than 55%, an initial dose of 10/40mg daily is recommended. Dosage adjustments should be made after checking blood lipid levels at intervals of more than 2 weeks.

Ingredients

Manufacturer
(주)보령

Efficacy & effects

Improvement of hypercholesterolemia (primary, mixed) and treatment of dyslipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • elevated total cholesterol
  • elevated LDL-cholesterol
  • elevated apo B protein
  • elevated triglycerides
  • elevated non-HDL-cholesterol
View approved original text

This medication is used for patients with primary hypercholesterolemia, especially heterozygous familial and non-familial hypercholesterolemia or mixed dyslipidemia. The treatment aims to lower levels of total cholesterol, LDL cholesterol, apo B protein, triglycerides, and non-HDL cholesterol while helping to increase HDL cholesterol levels. This treatment is carried out alongside dietary therapy to improve cholesterol and lipid-related levels. Consequently, it may contribute to the reduction of cardiovascular disease risk. This medication is effectively used to improve blood lipid status.

Dosage and Administration

Adult dosage

This medication is administered once daily regardless of meals. It is prescribed within a range of 10/5mg to 10/80mg daily. An initial dose of 10/5mg, 10/10mg, or 10/20mg daily is recommended. For patients requiring LDL cholesterol reduction of more than 55%, an initial dose of 10/40mg daily is recommended. Dosage adjustments should be made after checking blood lipid levels at intervals of more than 2 weeks.

Precautions

This medication may cause serious muscle problems; therefore, if symptoms of muscle pain or weakness occur, consult a physician immediately. If severe muscle pain or muscle damage is suspected, it may be necessary to discontinue treatment. This medication can affect liver function, so liver function tests should be performed before treatment and regularly monitored during treatment. Individuals who consume large amounts of alcohol or have a history of liver disease should use this medication with caution. Women who are pregnant or may become pregnant, as well as breastfeeding women, should not use this medication. It may be risky for certain liver disease patients or muscle disease patients, or when combined with certain drugs, so it is essential to consult a physician. Elderly patients are at higher risk for myopathy, so caution is necessary, but separate dosage adjustment is not required. Dizziness may occur when driving or operating machinery, so care should be taken. It is important to maintain a proper lifestyle improvement alongside dietary therapy while taking this medication. Additionally, there may be interactions with other medications, so if you are taking other drugs, it is vital to inform your physician.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest discomfort, difficulty breathing, jaundice, sudden and very severe headache, seizures, confusion, visual disturbances, paralysis, hematuria, severe generalized swelling, elevated blood pressure, intracranial aneurysm, restless legs syndrome, anaphylaxis, hepatitis, liver failure, mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), erythema multiforme, myopathy, rhabdomyolysis, severe muscle weakness

Mild side effects

  • Cough
  • oropharyngeal pain
  • dry mouth
  • abdominal discomfort
  • diarrhea
  • indigestion
  • nausea
  • dizziness
  • paresthesia
  • syncope
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  • tension-type headache
  • myalgia
  • spinal pain
  • muscle spasms
  • eye pruritus
  • giant papillary conjunctivitis
  • keratitis
  • posterior capsule opacification
  • blurred vision
  • COVID-19
  • nasopharyngitis
  • upper respiratory tract infection
  • chest discomfort
  • chest pain
  • acne
  • uterine leiomyoma
  • skin abrasions
  • ulnar fracture
  • seasonal allergies

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. Additionally, it is advisable to store the medication at room temperature between 1 to 30 degrees Celsius. Store it safely, avoiding extremely hot or cold places.

Appearance and packaging

Appearance

White oblong film-coated tablet

Package unit

30 tablets/bottle - 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.