Gluripitin Duo XR Tablets 5/1000 mg (Linagliptin, Metformin Hydrochloride)

Adult dose

This drug 5/1000 mg extended-release tablet is taken once daily, 1 tablet at a time. Patients taking this drug 2.5/1000 mg extended-release tablet should take 2 tablets simultaneously once daily. It should be taken with the evening meal, and increases in the dose of metformin hydrochloride should be gradual. To maintain its extended-release properties, do not split, crush, chew, or break the tablets, and the coating may be excreted in the stool, which is normal. Currently on metformin treatment.

This drug helps in controlling blood sugar levels. However, it should be noted that a rare but serious side effect called lactic acidosis, which involves excessive accumulation of lactic acid in the body, may occur, requiring caution. Especially in patients with poor kidney function or liver problems, serious infections, dehydration, or acute heart disease, this drug should not be used. Additionally, individuals with allergies to any of the ingredients in this drug should avoid taking it. This drug may cause hypoglycemia, so blood sugar levels should be monitored frequently, especially when used with other hypoglycemic agents or insulin. Excessive exercise, skipping meals, or alcohol consumption can also increase the risk of hypoglycemia, so caution is advised. Elderly patients with reduced kidney function or those with kidney disease must have regular kidney function tests and should discuss with their physician whether or not to take this drug. Adverse reactions such as acute pancreatitis or skin blistering, similar to bullous pemphigoid, may occur, so if sudden abdominal pain or skin changes occur during treatment, inform your doctor immediately. This drug should be swallowed whole and not chewed, crushed, or split, and the tablet coating may appear in bowel movements, but this is normal. Women who are pregnant or breastfeeding should avoid using this drug, and those planning to become pregnant should consult their doctor. Additionally, since this drug may interact with several medications, be sure to inform medical personnel if you are taking any other medications. If any sudden symptoms or adverse reactions occur during treatment with this drug, seek medical attention immediately.

Serious side effects

• Urticaria
• angioedema
• lactic acidosis
• pancreatitis
• bullous pemphigoid
• severe rash with fever
• blisters
• skin peeling
• mucosal pain in the mouth/eyes
• difficulty in breathing

Mild side effects

• Nasopharyngitis
• hypersensitivity reactions
• hypoglycemia
• taste abnormalities
• cough
• loss of appetite
• diarrhea
• constipation
• nausea
• vomiting

This drug may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius to preserve the drug's effectiveness.

Appearance

White oval extended-release film-coated tablets

Package unit

30 tablets per bottle