LinaMax Extended Release Tablet 2.5/1000 mg (Linagliptin, Metformin Hydrochloride)

Adult dose

This medication should be taken once daily with meals, preferably with the evening meal. To maintain its extended-release properties, do not split, crush, grind, or chew the tablets. For the 5/1000 mg extended release, take 1 tablet daily. For the 2.5/1000 mg extended release, take 2 tablets simultaneously once daily. The initial dosage consists of 5 mg linagliptin and 1000 mg metformin hydrochloride, and metformin...

This medication is primarily used for treating diabetes and aids in controlling blood glucose levels. However, it can rarely cause a dangerous condition known as lactic acidosis, hence it should not be administered to patients with severely impaired kidney function, poor liver function, or those experiencing acute infections or dehydration. Individuals allergic to any of the components in this medication, patients with type 1 diabetes, diabetic ketoacidosis, pregnant women, or those at risk of pregnancy should also avoid using this product. During treatment, hypoglycemic symptoms may appear, so it is important to regularly check blood glucose levels, especially when combined with other hypoglycemic agents or insulin. Elderly patients with diminished renal function or those taking medications that place stress on the kidneys require special caution and should undergo regular kidney function tests. This medication can be taken regardless of meals, but alcohol consumption should be avoided as it may increase the risk of lactic acidosis. Rare adverse effects such as acute pancreatitis or skin blistering similar to bullous pemphigoid may occur, so if severe abdominal pain or skin abnormalities develop, it is essential to notify a doctor immediately. For pregnant or breastfeeding patients, it is advisable to avoid using this medication, and those planning to become pregnant should consult their physician. Do not chew, crush, or break this medication; swallow it whole. The tablet shell may be excreted in feces, which is a normal occurrence. In the event of overdose, gastrointestinal disturbances or lactic acidosis may occur, so adherence to prescribed dosages is critical, and any abnormal symptoms should prompt an immediate visit to a healthcare facility. Finally, it is important to keep this medication out of reach of children and store it in a moisture-free environment.

Serious side effects

Rash, angioedema, lactic acidosis, pancreatitis, bullous pemphigoid, increased serum creatinine leading to renal impairment, acute kidney injury, acute cholangitis, acute cholecystitis, cholangitis, acute myocardial infarction, cardiac arrest, unstable angina, congestive heart failure, asthma, dyspnea, respiratory distress, chest tightness, severe edema, increased blood pressure, confusion, severe headache, paralysis, seizures, vision abnormalities, altered consciousness

Mild side effects

Nasopharyngitis, hypersensitivity reactions, taste disturbance, cough, decreased appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, oral ulcers, liver function abnormalities, hepatitis, itching, erythema, rash, severe arthralgia, increased lipase, elevated amylase, abnormal vitamin B12 absorption test results, hypoglycemia, angioedema, increased serum triglycerides, decreased hemoglobin, increased serum potassium levels, increased creatinine levels, increased creatine phosphokinase levels

Store this medication in a tightly closed container to prevent exposure to air or moisture. The safe storage temperature is between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness and prevents degradation.

Appearance

Oval-shaped extended release tablet, white to nearly white, engraved with P251 on one side

Package unit

28 tablets/box [7 tablets/PTP x 4], 30 tablets/bottle