Nexcolin Tablet 30 mg (Nisegrolin)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 2 ∼ 3 times a day before meals. Adjust the dose appropriately according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once a day before a meal. If the desired effect is not achieved at this dose, it may be increased to 60 mg. The dose may be reduced after symptoms improve. For patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This medication should not be used in certain patients. For example, individuals with allergies to this drug or ergot alkaloids, those with acute myocardial infarction or acute bleeding, those taking sympathomimetic drugs, those with very low heart rates, those who have not achieved hemostasis after intracranial bleeding, and those with orthostatic dysregulation should not take this medication. In addition, those with slightly low heart rates or renal function issues should be more cautious when using this medication. This medication may rarely cause gastrointestinal symptoms such as loss of appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, and dry mouth. Liver function tests may show elevated values, and cardiovascular abnormalities such as dizziness, orthostatic hypotension, hypertension, and hypotension may also occur. Neurological symptoms such as drowsiness, fatigue, headaches, and insomnia have also been reported rarely. Allergic reactions may manifest as skin rashes, hives, itching, flushing, and warmth, so caution is necessary. Post-marketing studies have reported new adverse reactions such as nightmares, mood changes, and dyspepsia. When taken with other medications that lower blood pressure, blood pressure may drop too low, so regular blood pressure monitoring is necessary. Additionally, this medication can affect uric acid metabolism, and caution should be exercised by those with gout or a history of gout. Care should be taken when driving or operating machinery after taking this medication. This medication is metabolized by specific enzymes (CYP450 2D6) in the liver, so it may interact with other drugs that utilize this enzyme. Women who are pregnant or may become pregnant should weigh the risks and benefits carefully when using this medication, and it is advisable to avoid use while breastfeeding or to discontinue breastfeeding. Elderly patients may have diminished physiological function, so caution should be exercised, including dosage reduction. Safety for pediatric patients has not yet been established. In cases of overdose, blood pressure may temporarily drop, so blood pressure changes should be monitored and appropriate actions taken. Finally, this medication should be stored out of reach of children, and it is safe to keep it sealed in its original container.

• Loss of appetite
• diarrhea
• constipation
• nausea
• vomiting
• sporadic upper abdominal pain or cramps
• thirst
• ALT elevation
• AST elevation
• dizziness

This medication should be stored in a sealed container to protect it from air and moisture, ideally at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the medicine's efficacy over time.

Appearance

Pale yellow round coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle