Medication info
Atovamibe A Tablet 10/20/5 mg (Ezetimibe, Atorvastatin, Amlodipine)

Atovamibe A Tablet 10/20/5 mg (Ezetimibe, Atorvastatin, Amlodipine)

Prescription medicationTablet경구
Ingredient · strength
Atorvastatin Calcium Trihydrate›21.7mg / 1 tabletAmlodipine Besylate›6.944mg / 1 tabletEzetimibe›10mg / 1 tablet
Manufacturer / importer
(주)유한양행
Appearance
Yellow oblong film-coated tablet
Packaging
30 tablets/box [(10 tablets/PTP x 3)]
Approval status
Active

MFDS item code 202400309 · Approved 2024.02.13

Summary

Main use
(Hypertension, Angina Pectoris) Improvement of myocardial ischemia and (Hypercholesterolemia) Improvement of dyslipidemia
Who takes it
Adults
Adult dose
The recommended dosage of this medication is one tablet once a day, taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). For amlodipine, adults take 5 mg orally once a day, which can be increased to a maximum of 10 mg daily based on the patient's response. The ezetimibe/atorvastatin combination is taken once daily, with a dosage range of 10/10 mg to 10/80 mg.

Ingredients

Manufacturer
(주)유한양행

Efficacy & effects

(Hypertension, Angina Pectoris) Improvement of myocardial ischemia and (Hypercholesterolemia) Improvement of dyslipidemia

  • Hypertension
  • fixed occlusion of the coronary artery
  • vascular spasms of the coronary vascular system
  • vasoconstriction
  • myocardial ischemia
  • primary hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
View approved original text

This medication is used for patients who need to take a combination of amlodipine and ezetimibe/atorvastatin. Amlodipine helps to treat hypertension and angina, especially myocardial ischemia caused by coronary vessel spasm or vasoconstriction. It is also effective in reducing the risk of hospitalization for patients with coronary heart disease and reducing the risk associated with vascular revascularization. The ezetimibe/atorvastatin combination improves blood cholesterol levels in patients with hypercholesterolemia and dyslipidemia and is also used to treat homozygous familial hypercholesterolemia. This combination plays an important role in controlling risk factors for cardiovascular disease, contributing to the improvement of cardiovascular health in patients.

How to take

Adult dose

The recommended dosage of this medication is one tablet once a day, taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). For amlodipine, adults take 5 mg orally once a day, which can be increased to a maximum of 10 mg daily based on the patient's response. The ezetimibe/atorvastatin combination is taken once daily, with a dosage range of 10/10 mg to 10/80 mg.

Precautions

This medication carries a risk of severe muscle-related issues, so if symptoms like severe muscle pain or weakness occur, you should consult a doctor immediately. Patients with hypersensitivity to any component of this medication, severely impaired liver function, muscle disorders, pregnant or nursing women should not use it. Patients with compromised liver function or a history of alcohol dependence, elderly patients, or those with impaired kidney function should use this medication with caution and undergo regular medical check-ups. This medication can elevate liver enzyme levels, so liver function tests should be conducted before and during treatment, and if symptoms of liver damage occur, use should be discontinued immediately. Since it may interact with other medications, inform your doctor or pharmacist if you are taking other drugs, especially certain antibiotics, antivirals, anticoagulants, or fibrate medications, as caution is needed when used in combination. If you experience symptoms such as muscle pain, muscle cramps, fatigue, or fever while taking this medication, inform healthcare professionals immediately for examination. Women of childbearing potential should use appropriate contraception to avoid pregnancy while taking this medication and should not take it if planning a pregnancy or already pregnant. Caution is required while driving or operating machinery as symptoms like dizziness may occur. This medication contains lactose, so patients with lactose intolerance or related genetic disorders should not take it. Regular blood tests and health monitoring should be conducted during the use of this medication, and if any abnormal symptoms arise, consult healthcare professionals immediately.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attack, respiratory abnormalities accompanied by coughing and fever, yellowing of the skin or eyes (jaundice), severe fatigue, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Headache
  • constipation
  • dyspepsia
  • arthralgia
  • fatigue
  • edema
  • dry eyes
  • ventricular tachycardia
  • chest pain
  • diarrhea
Show 30 more
  • nausea
  • myalgia
  • dizziness
  • nightmares
  • insomnia
  • vomiting
  • itching
  • rash
  • hair loss
  • sweating
  • hives
  • thrombocytopenia
  • anemia
  • cough
  • epistaxis
  • upper respiratory infection
  • pharyngitis
  • malaise
  • vasculoneurotic edema
  • facial edema
  • fever
  • neck stiffness
  • heaviness in the head
  • heat sensation
  • impaired glucose tolerance
  • weakness
  • chest pain
  • angina
  • hives
  • hyperhidrosis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container, away from air and moisture, at a safe temperature between 1 to 30 degrees Celsius. Proper storage will maintain the medication's efficacy and prevent deterioration.

Appearance and packaging

Appearance

Yellow oblong film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.