Medication info
Nisercod Tablet 30 mg (Nisergoline)

Nisercod Tablet 30 mg (Nisergoline)

Prescription medicationTabletOral
Ingredient · strength
Nicergoline›30mg / 1 tablet
Manufacturer / importer
Daewong Bio Co., Ltd.
Appearance
Yellow round film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202400268 · Approved 2024.02.06 · Insurance code 694004170

Summary

Main use
Improvement of dementia syndrome and decreased motivation; relief of atherosclerotic headaches in older adults; adjunctive treatment of hypertension
Who takes it
Adults
Adult dose
* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 2 ∼ 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. For patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

Ingredients

Manufacturer
Daewong Bio Co., Ltd.

Efficacy & effects

Improvement of dementia syndrome and decreased motivation; relief of atherosclerotic headaches in older adults; adjunctive treatment of hypertension

  • Decreased motivation
  • geriatric arteriosclerotic headaches
  • memory impairment
  • concentration disorders
  • judgment disorders
  • lack of initiative
View approved original text

This medication helps improve motivation decline in chronic cerebral circulation disorders caused by cerebral infarction sequelae. It is also used as an adjunct for alleviating geriatric arteriosclerotic headaches and treating hypertension. The 30 mg dosage is effective in treating dementia symptoms such as memory impairment, concentration deficits, decreased judgment, and lack of initiative in degenerative vascular dementia and mixed dementia. Overall, it helps improve brain function and maintain vascular health, thereby improving the quality of life of patients.

How to take

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 2 ∼ 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. For patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

Precautions

This medication should not be used in certain patients. For example, individuals allergic to this medication or ergot alkaloids should not take it. Additionally, patients with acute myocardial infarction or acute hemorrhage, as well as those currently taking sympathomimetics, should also avoid using this medication. People with significantly reduced heart rates, especially those with less than 50 beats per minute, and patients who have not completed hemostasis after intracranial hemorrhage, as well as those with orthostatic regulation disorders should avoid this medication. Patients with mild bradycardia or renal function issues should take this medication with caution. Occasionally, symptoms such as dyspepsia, diarrhea, constipation, nausea, vomiting, abdominal pain, and dry mouth may occur. Rarely, liver enzyme levels may increase, so monitoring liver health is necessary. Symptoms such as dizziness, blood pressure changes, orthostatic hypotension, headaches, drowsiness, fatigue, and insomnia may also occur, requiring caution. Additionally, allergic reactions such as skin rashes or itching may arise. Since this medication has blood pressure-lowering effects, blood pressure should be monitored frequently when taken with other antihypertensive medications. Patients with a history of gout should be cautious as it may affect uric acid levels. After taking this medication, caution is advised when driving or operating machinery. This medication is metabolized in the liver via specific enzymes, so interactions may occur when taken with other medications that utilize those enzymes. Pregnant or potentially pregnant women should only take this medication under medical supervision due to potential risks. If breastfeeding, it is advisable to avoid this medication or discontinue breastfeeding since it may be excreted in breast milk. Elderly patients may require dosage adjustments due to decreased bodily functions. Safety in children has not been established, so use is not recommended.  In case of overdose, blood pressure may temporarily decrease, so blood pressure changes should be carefully monitored and appropriate measures taken. This medication should be kept out of reach of children and stored securely in its original container.

Side effects

  • Loss of appetite
  • diarrhea
  • constipation
  • nausea
  • vomiting
  • episodic upper abdominal pain
  • cramps
  • thirst
  • ALT elevation
  • AST elevation
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  • dizziness
  • orthostatic intolerance
  • hypertension
  • increased serum uric acid
  • hypotension
  • drowsiness
  • fatigue
  • headache
  • tinnitus
  • tiredness
  • insomnia
  • rash
  • urticaria
  • itching
  • flushing
  • heat sensation
  • nightmares
  • mood changes
  • indigestion

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is best to keep it at a temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.