Medication info
Neogolrin 30 mg (Nisergoline)

Neogolrin 30 mg (Nisergoline)

Prescription medicationTabletOral
Ingredient · strength
Nicergoline›30mg / 1 tablet
Manufacturer / importer
SaeHan Pharmaceutical Co., Ltd.
Appearance
Yellow round film-coated tablets
Packaging
Bottle packaging - 30 tablets/bottle, Bottle packaging - 100 tablets/bottle
Approval status
Active

MFDS item code 202400222 · Approved 2024.01.30 · Insurance code 651301020

Summary

Main use
Treatment of dementia syndrome (memory impairment, difficulty concentrating, etc.)
Who takes it
Adults
Adult dose
* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 2 ∼ 3 times a day before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before meals. If the desired effect is not achieved at this dose, it may be increased to 60 mg. The dose may be reduced after symptoms improve. In patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

Ingredients

Manufacturer
SaeHan Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of dementia syndrome (memory impairment, difficulty concentrating, etc.)

  • Decrease in motivation
  • elderly atherosclerotic headache
  • impaired memory
  • concentration difficulties
  • judgment impairment
  • lack of initiative
View approved original text

This medication helps improve the decrease in motivation associated with chronic cerebral circulation disorders due to sequelae of cerebral infarction. It is also used to alleviate atherosclerotic headache, which is common in elderly patients, and serves as an adjunctive treatment in hypertension. The 30 mg formulation is effective in treating the main symptoms of primary degenerative vascular dementia and mixed dementia, such as memory impairment, concentration difficulties, judgment decline, and lack of initiative. This medication contributes to improving the quality of life of patients by enhancing brain function and cognitive abilities.

How to take

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 2 ∼ 3 times a day before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before meals. If the desired effect is not achieved at this dose, it may be increased to 60 mg. The dose may be reduced after symptoms improve. In patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

Precautions

This medication should not be used in certain patients. Those allergic to this medication or ergot alkaloids should not take it. Patients with acute cardiac issues or acute bleeding should also refrain from taking this drug. Patients currently on sympathomimetic medications or those with very slow heart rates should avoid this drug as well. Patients with unresolved hemostasis after cerebral hemorrhage or those with orthostatic hypotension should not use this medication. Patients with mild bradycardia or impaired renal function should take this medication cautiously. Rarely, the medication may cause symptoms such as dyspepsia, diarrhea, constipation, nausea, vomiting, abdominal pain, or dry mouth. Liver function test values may increase, so monitoring is necessary. Dizziness, blood pressure changes, drowsiness, headache, fatigue, and insomnia may also occur infrequently. Allergic reactions may cause skin rashes or itching. When taken with other antihypertensive medications, blood pressure may drop too low, so regular monitoring is advised. The drug may influence uric acid levels, so caution is warranted for individuals with a history of gout. After taking this medication, caution should be exercised when driving or operating machinery. This drug is metabolized in the liver, hence there is potential for interaction with other drugs. Women who are pregnant or may become pregnant should consult a doctor, as the use of this medication may pose risks. Nursing mothers should avoid this medication or stop breastfeeding, as it could be transferred to breast milk. Older patients may have decreased bodily function, thus appropriate dosage adjustments are advised when taking this medication. The safety of this medication in children has not been established, so its use is not recommended. In case of overdose, blood pressure may drop sharply, so immediate medical attention should be sought if symptoms occur. This medication should be kept out of reach of children and stored in its original container.

Side effects

  • Loss of appetite
  • diarrhea
  • constipation
  • nausea
  • vomiting
  • scattered upper abdominal pain or cramps
  • dry mouth
  • ALT elevation
  • AST elevation
  • dizziness
Show 18 more
  • orthostatic hypotension
  • hypertension
  • increased blood uric acid
  • blood pressure reduction
  • drowsiness
  • lethargy
  • headache
  • tinnitus
  • fatigue
  • insomnia
  • rash
  • urticaria
  • itching
  • flushing
  • warmth
  • nightmares
  • mood changes
  • dyspepsia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from exposure to air and moisture. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius. This helps preserve the drug's effectiveness and safety over time.

Appearance and packaging

Appearance

Yellow round film-coated tablets

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.