Securin Tablets 30mg (Nisergoline)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally per dose, 2 ∼ 3 times daily before meals. The dose may be adjusted as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. For patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This medication should not be used in certain patients. Those who are allergic to this medication or ergot alkaloids, have acute myocardial infarction or acute bleeding, are taking sympathomimetic drugs, have significantly slow heart rates, have not completed hemostasis after intracranial bleeding, or have orthostatic dysregulation should not take this medication. Patients with mild heart rate reduction or impaired kidney function should take this medication cautiously. During use, rare symptoms may occur, including dyspepsia, diarrhea, constipation, nausea, vomiting, abdominal pain, and dry mouth. Abnormal liver function, dizziness, blood pressure fluctuations, drowsiness, headaches, fatigue, insomnia, allergic skin reactions may also occur rarely. When taken with antihypertensive medications, blood pressure may become too low, so blood pressure should be monitored frequently. Additionally, it may affect uric acid levels, so those with gout or hyperuricemia should take caution. After taking this medication, one should be cautious when driving or operating machinery. As this medication is metabolized in the liver, it may interact with other medications, so caution should be taken when combining it with other drugs being taken. Pregnant women or those who may become pregnant should consult a doctor before taking this medication, and nursing mothers are advised to either avoid it or discontinue breastfeeding. The elderly may have decreased physiological function, so dosage adjustments may be necessary. Safety in children is not established, so use in the pediatric population should be approached with caution. If this medication is taken in excess, blood pressure may temporarily drop, so periodic monitoring of blood pressure is required along with necessary measures. This medication should be kept out of reach of children and stored tightly in its original container.

• Loss of appetite
• diarrhea
• constipation
• nausea
• vomiting
• localized upper abdominal pain
• cramps
• thirst
• ALT elevation
• AST elevation

This medication should be stored in a sealed container that blocks light, and the recommended storage temperature is between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and prevent it from degrading.

Appearance

Yellow round film-coated tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle