Atovamibe A Tablets 10/10/10 mg (Ezetimibe, Atorvastatin, Amlodipine)

Adult dose

The recommended dosage for this medication is one tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning) if possible. Amlodipine is administered orally as 5 mg once daily, and the dose may be increased up to 10 mg daily depending on the patient's response. Adjustments should be made according to age and symptoms. The ezetimibe/atorvastatin combination is administered once daily regardless of meals.

This medication carries the risk of rhabdomyolysis, a rare condition where muscle cells are destroyed, potentially leading to kidney problems, due to atorvastatin, one of its active ingredients. Therefore, if acute muscle pain or weakness occurs, consultation with a doctor should be sought immediately, and the drug should be discontinued temporarily if there are risk factors like severe infections or hypotension. This medication should not be used in patients with severe liver impairment, active liver diseases, muscle diseases, pregnant or lactating women. It is also contraindicated in patients with allergies to the active ingredients or components of this drug. Caution should be exercised when administering this drug to patients with a history of alcohol abuse, liver disease, impaired kidney function, hypothyroidism, and elderly patients who are at heightened risk for myopathy. Liver function abnormalities may occur during treatment with this medication, so regular liver function tests should be performed both before and during treatment, and if symptoms of hepatitis or jaundice occur, the medication should be discontinued immediately. This drug can interact with various other medications, so if patients are taking CYP3A4 inhibitors, cyclosporine, HIV protease inhibitors, antibiotics, or some antiviral drugs, they should consult their doctor as dosage adjustments or discontinuation may be necessary. If symptoms like muscle pain, cramps, or weakness occur during treatment, patients should notify their doctor immediately and undergo evaluation, and if severe, the medication should be discontinued. Women of childbearing potential should use appropriate contraception to avoid pregnancy while taking this medication and should not take it if pregnant or potentially pregnant. Additionally, this medication may cause dizziness or drowsiness, necessitating caution when driving or operating machinery.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes accompanied by high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, liver abnormalities (jaundice), sudden and severe headaches,

Mild side effects

• Headache
• constipation
• dyspepsia
• chest pain
• edema
• dry eyes
• ingrown toenails
• palpitations
• joint pain
• fatigue

This medication should be stored in a sealed container to protect it from air and moisture, ideally at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain its effectiveness and prevents degradation.

Appearance

Pale yellow film-coated tablets, rectangular

Package unit

30 tablets/box [(10 tablets/PTP X 3)]