Medication info
Chamatrijejeong (Trimebutine Maleate)

Chamatrijejeong (Trimebutine Maleate)

OTC medicationTablet경구
Ingredient · strength
Trimebutine Maleate›100mg / 1 tablet
Manufacturer / importer
메딕스제약(주)
Appearance
White round tablet
Packaging
PTP - 20 tablets/box [(10 tablets/PTP * 2)]
Approval status
Active

MFDS item code 202303191 · Notified 2023.11.22

Summary

Main use
Improvement of gastroesophageal reflux and gastrointestinal disorders (abdominal pain, dyspepsia), relief of irritable bowel syndrome, treatment of pediatric vomiting and intestinal disorders
Who takes it
Adults
Adult dose
As trimebutine maleate, take 100-200mg orally three times a day before meals. Adjust dosage as necessary based on age and symptoms.

Ingredients

Manufacturer
메딕스제약(주)

Efficacy & effects

Improvement of gastroesophageal reflux and gastrointestinal disorders (abdominal pain, dyspepsia), relief of irritable bowel syndrome, treatment of pediatric vomiting and intestinal disorders

  • Gastroesophageal reflux
  • hiatal hernia
  • gastric duodenitis
  • gastric duodenal ulcer
  • dyspepsia
  • abdominal pain
  • nausea
  • vomiting
  • irritable bowel syndrome
  • colonic spasms
  • habitual vomiting
  • non-infectious intestinal transit disorders
View approved original text

This medication helps relieve symptoms of gastrointestinal diseases such as gastroesophageal reflux and hiatal hernia, as well as abdominal pain, dyspepsia, nausea, and vomiting caused by inflammation and ulcers in the stomach and duodenum. It also improves abdominal discomfort due to irritable bowel syndrome and colonic spasms, and is effective in the treatment of habitual vomiting in children and non-infectious intestinal transit disorders (constipation, diarrhea). It is used to treat various digestive-related problems and improve symptoms.

How to take

Adult dose

As trimebutine maleate, take 100-200mg orally three times a day before meals. Adjust dosage as necessary based on age and symptoms.

Precautions

This medication may affect the gastrointestinal tract, and rare symptoms such as constipation, diarrhea, gas sounds in the intestines, nausea, vomiting, dyspepsia, thirst, and a numbing sensation in the mouth may occur. Additionally, rare heart-related symptoms such as palpitations may occur. It may also affect the central nervous system, resulting in fatigue, drowsiness, dizziness, lethargy, and headache, which can occur rarely. It may impact liver function, leading to elevated liver enzyme levels. If skin rashes or other hypersensitivity reactions occur, the medication should be discontinued. The safety of this medication has not been adequately established during pregnancy, so women who are pregnant or may become pregnant should only use it when the benefits outweigh the risks. Women who are breastfeeding should also avoid using this medication if possible, and it is advisable to stop breastfeeding if necessary.

Side effects and when to seek care immediately

Mild side effects

  • Constipation
  • diarrhea
  • abdominal sounds (gas sounds)
  • nausea
  • vomiting
  • dyspepsia
  • thirst
  • numbness in the mouth
  • palpitations
  • fatigue
Show 7 more
  • drowsiness
  • dizziness
  • lethargy
  • headache
  • increased GOT
  • GPT levels
  • rash

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is safest to store it at room temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

White round tablet

Package unit

PTP - 20 tablets/box [(10 tablets/PTP * 2)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

  • QIs it used for children with habitual vomiting?

    The efficacy includes habitual vomiting and non-infectious gastrointestinal disorders (constipation, diarrhea) for pediatric diseases. However, the provided dosage only includes adult dosages, so for children, the dosage should be determined in consultation with a doctor or pharmacist.

    Answers 1 · 2026.09.14

  • QShould I avoid taking it after meals?

    The approval information states that adults should take 100-200 mg three times a day before meals. If it is difficult to take due to meal times, please discuss with a pharmacist about adjusting the timing instead of making changes on your own.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.