Nebivolol-Rosuvastatin Tablets 1.25/10 mg (Nebivolol, Rosuvastatin)

Adult dose

This medication is administered as a convenient option for patients who are currently taking both nebivolol and rosuvastatin, dosed as one tablet taken once daily.

This medication must not be used in certain patients. For example, it should not be administered to patients who are allergic to any of its components, those with severely impaired liver function, patients with abnormally slow heart rates, or those with severe heart failure or low blood pressure. Patients with severe kidney impairment or a history of bronchial asthma should also avoid using this drug. It should not be administered to pregnant or nursing women or to fertile women who are not using appropriate contraception. Caution is also required for patients with a history of muscle diseases or those at high risk of muscle damage when used in combination with specific medications. This medication should be used with caution in patients with chronic lung disease, heart failure, peripheral circulation disorders, thyroid abnormalities, or diabetes. Especially because muscle-related side effects may occur, if symptoms such as muscle pain or weakness appear, it is essential to consult a physician immediately. Furthermore, if liver dysfunction is suspected, it is important to repeat liver enzyme tests to confirm this. This drug may interact with multiple medications; thus, patients should inform their physician or pharmacist if they are taking other drugs. Caution is particularly required when taken in combination with calcium channel blockers, antiarrhythmic agents, central nervous system medications, and diabetes treatments. During pregnancy, this medication should not be administered due to potential risks to the fetus, and similarly, it is advisable not to use it while breastfeeding as it may be excreted in breast milk. In elderly patients, starting with a low dose and careful administration is crucial. Overdosage can result in symptoms such as bradycardia, hypotension, and respiratory distress, which require immediate medical attention. While taking this medication, dizziness may occur; therefore, caution is advised when driving or operating machinery, and it should be kept out of reach of children.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucous membranes, shortness of breath or trouble breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes, extreme fatigue, sudden and severe headache, lightning headache, seizures, confusion of consciousness, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

• Eye discharge
• upper abdominal discomfort
• gastritis
• gastroesophageal reflux disease
• chest pain
• nasopharyngitis
• flu
• increased CK
• increased ALT
• increased AST

This medication should be kept in a tightly closed container to protect it from air and moisture. It is important to maintain storage temperatures between 1 degree and 30 degrees Celsius. By storing it this way, the effectiveness and safety of the drug can be well maintained.

Appearance

Pale yellow round film-coated tablet

Package unit

30 tablets/bottle