Medication info
Serizine (Cetirizine Hydrochloride)

Serizine (Cetirizine Hydrochloride)

OTC medicationTablet
Ingredient · strength
Cetirizine Hydrochloride›10mg / 1 tablet
Manufacturer / importer
메딕스제약(주)
Appearance
White, rectangular, film-coated tablets
Packaging
PTP - 10 tablets/box [(10 tablets/PTP *1)], PTP - 20 tablets/box [(10 tablets/PTP *2)]
Approval status
Active

MFDS item code 202303056 · Notified 2023.11.02

Summary

Main use
Improvement of allergy symptoms such as allergic rhinitis and conjunctivitis, chronic urticaria.
Who uses it
Adults · Children
Adult dosage
Adults and children aged 6 years and older should take 10mg of cetirizine hydrochloride orally once daily before bedtime. Patients sensitive to adverse effects may take 5mg split between morning and evening doses. Patients with renal impairment should adjust dosage and dosing intervals according to creatinine clearance.
Children's dosage
For children aged 6 years and older, take the same as adults, 10mg orally once daily before bedtime. Children with kidney impairment should have their dosage adjusted individually based on renal clearance and body weight.

Ingredients

Manufacturer
메딕스제약(주)

Efficacy & effects

Improvement of allergy symptoms such as allergic rhinitis and conjunctivitis, chronic urticaria.

  • Seasonal allergic rhinitis
  • perennial allergic rhinitis
  • allergic conjunctivitis
  • chronic idiopathic urticaria
  • itching of the skin
  • eczema
  • dermatitis
View approved original text

This medication is used for seasonal and perennial allergic rhinitis, allergic conjunctivitis, chronic idiopathic urticaria, and itching of the skin. It is also used in combination with topical hydrocortisone for the treatment of skin conditions such as eczema and dermatitis. It helps alleviate the symptoms of these conditions and improves the quality of life for patients.

Dosage and Administration

Adult dosage

Adults and children aged 6 years and older should take 10mg of cetirizine hydrochloride orally once daily before bedtime. Patients sensitive to adverse effects may take 5mg split between morning and evening doses. Patients with renal impairment should adjust dosage and dosing intervals according to creatinine clearance.

Children's dosage

For children aged 6 years and older, take the same as adults, 10mg orally once daily before bedtime. Children with kidney impairment should have their dosage adjusted individually based on renal clearance and body weight.

Precautions

This medication should not be taken by patients who are allergic to certain components, have severely impaired kidney function, or are under 6 years of age. Additionally, individuals with genetic problems such as lactose intolerance or lactase deficiency, or glucose-galactose malabsorption should not use this medication. While taking this medication, individuals should not take certain drugs, such as theophylline or ritonavir. Avoid taking this medication with alcohol and use caution with other antihistamines. Patients with impaired kidney or liver function, elderly patients, patients with epilepsy, and women who are pregnant or breastfeeding should consult a physician or pharmacist before taking this medication. Particularly, this medication is excreted through the kidneys, so elderly patients with reduced kidney function should start with a low dose and be closely monitored. This medication requires caution in patients with conditions causing poor urine output. While no major side effects have been reported during pregnancy, it is advisable to consult a physician for safety, and breastfeeding women should exercise caution as it may affect the baby. Overdosage of this medication can lead to symptoms such as confusion, drowsiness, dizziness, headache, and irregular heartbeat; in such cases, immediate consultation with medical personnel is necessary. Various side effects such as drowsiness, headache, gastrointestinal disturbances, skin rash, and liver function abnormalities may occur during use, and if abnormal symptoms appear, it is essential to consult a specialist promptly. It is advisable to temporarily discontinue this medication prior to an allergy test, and caution should be exercised while driving or operating machinery. This medication can be taken with food without significantly altering its efficacy, but the absorption rate may be slightly delayed. Finally, this medication should be stored out of reach of children and kept in its original container for safety.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, pain on mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Confusion
  • diarrhea
  • dizziness
  • fatigue
  • headache
  • malaise
  • pupil dilation
  • itching
  • restlessness
  • sedation
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  • drowsiness
  • stupor
  • tachycardia
  • tremors
  • urinary retention
  • sleepiness
  • occasional malaise
  • numbness
  • weakness
  • sensory abnormalities
  • rarely mild and temporary lethargy
  • heaviness in head
  • excitability
  • seizures
  • movement disorders
  • muscle tension abnormalities
  • fainting
  • aggressiveness
  • depression
  • hallucinations
  • insomnia
  • tics
  • amnesia
  • memory impairment
  • suicidal ideation
  • nightmares
  • thirst

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture; it should be stored in a tightly sealed container. It is recommended to maintain storage temperatures between 1 degree and 30 degrees Celsius at room temperature to safely preserve the drug's efficacy.

Appearance and packaging

Appearance

White, rectangular, film-coated tablets

Package unit

PTP - 10 tablets/box [(10 tablets/PTP *1)], PTP - 20 tablets/box [(10 tablets/PTP *2)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.