Xoneal Tablet 5/160/2.5 Milligrams

Adult dose

Take 1 tablet daily with water. It is recommended to take it at the same time each day (e.g., before breakfast). The dosage of amlodipine/valsartan combination therapy and rosuvastatin should be individualized for each patient. Amlodipine/valsartan combination therapy should be administered as follows: - 5/80 mg: For patients whose blood pressure is inadequately controlled on monotherapy with either 5 mg of amlodipine or 80 mg of valsartan.

This medication should not be taken during pregnancy, especially in the second and third trimesters, as it may cause serious harm to the fetus and newborn. If pregnancy is confirmed, use should be discontinued immediately. It should not be used in patients with hypersensitivity to certain components, in pregnant or breastfeeding women, or in patients with severe liver or kidney disease. Patients who are deficient in sodium or body fluids may experience hypotension, so their status should be carefully checked and monitored before administration. Patients with high potassium levels or those on other medications that may raise potassium levels should frequently monitor potassium levels and take caution. In patients with renal artery stenosis or those who have recently undergone kidney transplants, renal function changes should be closely observed when administering this drug. If signs of angioedema (airway obstruction or facial swelling) occur, use should be discontinued immediately and should not be re-administered. Patients with heart failure or those who have experienced a myocardial infarction need careful observation, including renal function assessments, as there is an increased risk of angina or worsening myocardial infarction in patients with acute myocardial infarction. Muscle-related side effects (myalgia, myopathy, rhabdomyolysis) can occur, so any symptoms of muscle pain or weakness should be reported to a healthcare provider immediately, and blood tests may be conducted if necessary. This medication may affect liver function, so it should be discontinued immediately if any signs of liver dysfunction occur. Patients with a history of liver disease are recommended to have liver function tests prior to taking this medication. Dizziness or fatigue may occur when driving or operating machinery, so caution is advised. This drug may interact with multiple medications, so patients should inform their doctor or pharmacist of any other medications they are taking. Pregnant or potentially pregnant women, as well as breastfeeding mothers, should not take this medication, and proper contraceptive methods should be used if planning to become pregnant. Its efficacy and safety in children under 18 years of age have not been established, so its use is not recommended in this population. No dosage adjustment is needed for the elderly, but older patients may be more sensitive to medications and should take caution in their usage. In cases of overdose, severe hypotension or cardiac issues may occur, necessitating an immediate visit to a medical facility for appropriate treatment.

Serious side effects

Urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes (mouth/eyes), shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary output changes

Mild side effects

• Peripheral edema
• warmth sensation
• ALT increase
• AST increase
• blood creatinine increase
• flank pain
• throat pain
• dizziness
• sensory reduction
• nasopharyngitis

Store this medication in a sealed container to protect it from air and moisture. It is advisable to keep the storage temperature between 1 and 30 degrees Celsius.

Appearance

Orange, egg-shaped film-coated tablet

Package unit

30 tablets per bottle