Exoneal Tablet 5/80/2.5 mg

Adult dose

This medication is taken once daily, 1 tablet with water. It is recommended to take it at the same time every day (for example, before breakfast). In the case of the amlodipine/valsartan combination, doses of 5/80 mg, 5/160 mg, and 10/160 mg are given depending on patients for whom blood pressure is not adequately controlled by monotherapy. Rosuvastatin should start at 2.5 or 5 mg once a day and adjusted as needed.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy; therefore, it should be discontinued immediately upon confirmation of pregnancy. It should not be used in patients with hypersensitivity to any of its components, in pregnant or breastfeeding women, or in patients with severe liver or kidney impairment. Patients with sodium or fluid depletion may experience hypotension, so their status should be checked before taking this medication, and blood pressure and symptoms should be closely monitored during use. It is important to frequently check potassium levels when used in patients with high potassium levels or in conjunction with medications that may increase potassium. It should be administered with caution to patients with impaired kidney function or those who have undergone kidney transplantation, and it should be discontinued immediately if allergic reactions such as angioedema occur. Patients with heart failure or after myocardial infarction should have their kidney function assessed regularly while taking this medication, and caution is warranted in patients with acute myocardial infarction. Elderly patients may be more sensitive to this medication, so starting at a lower dose and monitoring their condition is recommended. This medication can affect liver and kidney function, so regular blood tests and liver function tests are necessary. If symptoms like muscle pain, muscle weakness, fatigue, rash, dizziness, or sensory disturbances occur, consult a doctor immediately, especially since muscle-related symptoms can indicate serious side effects. This medication may interact with other drugs, so make sure to inform your doctor or pharmacist of any other medications you are taking. Caution is advised when driving or operating machinery as dizziness or fatigue may occur. Women who are pregnant or planning to become pregnant should not take this medication, and breastfeeding mothers should also avoid it. This medication is not recommended for children and adolescents as safety and efficacy have not been established.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, respiratory problems, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden

Mild side effects

• Peripheral edema
• warmth
• increase in ALT
• increase in AST
• increase in blood creatinine
• flank pain
• sore throat
• dizziness
• sensory impairment
• rhinopharyngitis

This medication must be stored in a tightly sealed container to protect it from air and humidity, and it is safe to keep it at room temperature between 1 to 30 degrees Celsius. This is to maintain the drug's effectiveness and prevent degradation.

Appearance

Light yellow oval film-coated tablet

Package unit

30 tablets/bottle