Jardimet Tablet 12.5/850 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

The recommended dosage for this medication is one tablet, twice daily. The dosage should be determined based on each patient's current treatment regimen, efficacy, and tolerability, without exceeding 25 mg of empagliflozin and 2000 mg of metformin. For patients who cannot achieve adequate blood sugar control with monotherapy of metformin or other medications like insulin, the recommended dosage is 5 mg of empagliflozin twice daily (total daily dose of 10 mg), and

This medication can cause a rare but very serious side effect known as severe lactic acidosis, and should not be used in patients with impaired kidney function, serious infections, or dehydration. Caution is also necessary when taking this medication with other diabetes drugs such as insulin or sulfonylureas, as it may increase the risk of hypoglycemia. Patients with a certain level of reduced kidney function, acute heart failure, acute myocardial infarction, or those facing specific acute illnesses or surgeries should not take this medication. During the course of this medication, regular kidney function tests should be performed, especially in elderly patients or those with slightly reduced kidney function. Patients at risk of fluid loss, such as those with severe vomiting or diarrhea, should consider temporarily discontinuing this medication. This medication may increase the risk of urinary tract infections and genital infections, so if symptoms of infection occur, one should immediately inform healthcare professionals and seek treatment. Pregnant women, those who may become pregnant, and nursing mothers should not take this medication, and if breastfeeding, should discontinue nursing. Excessive alcohol consumption should be avoided while taking this medication, as alcohol can increase the risk of side effects. Additionally, this medication may increase the risk of hypoglycemia when used with other blood sugar-lowering drugs, so dosage adjustments should be discussed with a healthcare professional. In preparation for surgery, this medication should be discontinued 48 hours before the procedure, and it can be resumed only after kidney function has returned to normal post-surgery. This medication is not recommended for children under 18, and dosage adjustments may be necessary for elderly patients based on their kidney function. Finally, during the course of this medication, if any symptoms change or unusual reactions occur, one should immediately consult a doctor to receive appropriate measures.

Serious side effects

Hives, angioedema, perineal necrosis, ketoacidosis, lactic acidosis, vascular stent thrombosis, cerebral infarction, acute kidney injury, acute pyelonephritis, pyelonephritis and urinary sepsis, myocardial infarction, heart failure, liver abnormalities (hepatitis, autoimmune hepatitis, acute cholecystitis), severe hypoglycemia, severe edema, severe allergic reactions, severe skin reactions, serious neurological symptoms (headache, seizures, consciousness confusion, visual disturbances, paralysis

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, at room temperatures between 1 to 30 degrees Celsius. This will help maintain the efficacy of the medication and prevent degradation.

Appearance

Pinkish white, biconvex, oval film-coated tablet

Package unit

60 tablets/box [10 tablets/PTP x 6], 10 tablets/box [10 tablets/PTP x 1], 60 tablets/bottle, 30 tablets/bottle