Empagliflozin Metformin Duo Tablet 12.5/1000 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

The recommended dosage of this medication is 1 tablet once, 2 times a day. The dosage should be determined considering each patient’s current treatment regimen, efficacy, and tolerability, not exceeding empagliflozin 25 mg and metformin 2000 mg. Patients who cannot achieve adequate blood sugar control with metformin alone or in combination with other medications such as insulin should take empagliflozin 5 mg twice a day (total daily dose of 10 mg) together with their usual metformin dose.

This medication helps control blood sugar by combining two active ingredients that lower blood sugar levels. Caution should be exercised as there is a risk of severe lactic acidosis, a rare side effect that can occur while taking this medication. Lactic acidosis can lead to serious conditions due to the accumulation of lactic acid in the body. Additionally, if used in combination with insulin or other diabetes medications, there may be symptoms of hypoglycemia, so blood sugar changes should be monitored closely. Patients with moderate to severe renal impairment, acute kidney issues, severe infections, or heart problems should not take this medication for safety reasons. If an iodine contrast agent examination is planned, it is necessary to discontinue medication for a certain period before and after the exam and resume only after renal function has been confirmed. Pregnant or breastfeeding women should avoid using this medication. This medication can cause fluid volume loss, so patients with dehydration or low blood pressure should be cautious. During treatment, urinary or genital infections may occur, and symptoms should be reported to healthcare providers immediately. Long-term use may lower vitamin B12 levels; therefore, regular blood tests are recommended. In case of an overdose, blood dialysis may be required, so the dosage must be strictly adhered to. Finally, this medication is not recommended for children, and elderly patients should have their renal function monitored regularly during treatment.

Serious side effects

• Hives
• angioedema
• ketoacidosis
• lactic acidosis
• perineal necrosis
• cerebral infarction
• myocardial infarction
• acute kidney injury
• pyelonephritis
• urosepsis

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. This will help preserve the medication's effectiveness for a long time and ensure safe use.

Appearance

Biconvex oval film-coated tablet with a dark brownish purple color

Package unit

10 tablets/box [10 tablets/PTP x 1], 60 tablets/box [10 tablets/PTP x 6], 60 tablets/bottle, 30 tablets/bottle