Vildagliptin-Metformin Hydrochloride Tablet 50/500 mg (Vildagliptin, Metformin Hydrochloride)

Adult dose

The dosage of this medication should be individualized based on efficacy and tolerability within the limits of 100 mg vildagliptin and 2000 mg metformin. Daily doses of more than 100 mg of vildagliptin are not recommended. Administering with food or shortly after meals can reduce gastrointestinal adverse reactions associated with metformin. 1. For patients with no prior experience of diabetes medication treatment and insufficient blood sugar control with monotherapy:

This drug is used for the treatment of diabetes and helps in blood sugar control. However, this drug should not be used in patients with severely impaired kidney function or severe heart failure. Patients with acute cardiac issues, serious infections, or severe liver dysfunction should also avoid this medication. This drug can cause a rare but serious side effect known as lactic acidosis, which is a condition resulting from excessive accumulation of lactic acid in the body. Symptoms of lactic acidosis include abdominal pain, muscle pain, difficulty breathing, lethargy, hypothermia, and coma, and if these symptoms occur, immediate medical attention should be sought. It is important to avoid alcohol consumption while taking this medication, and to discontinue and consult a doctor if dehydration, severe diarrhea, or vomiting occurs. If a surgical procedure or a contrast agent test is to be conducted, this medication should be stopped for a certain period, and resumed only after confirming normal kidney function. It is safe for pregnant or breastfeeding women to avoid this medication. This drug can cause hypoglycemia, so caution is needed especially when taken with other hypoglycemic agents or when meals are skipped. During treatment, symptoms such as dizziness, headaches, or nausea may occur, and if severe, a doctor should be consulted. Additionally, regular monitoring of liver and kidney function while taking this medication is recommended. Elderly patients may experience decreased kidney function, so dose adjustments and regular examinations are required. Patients should also regularly check their blood sugar and hemoglobin A1c levels to evaluate treatment effectiveness. In case of overdose, immediate medical attention should be sought, as this drug can be partially removed through hemodialysis. Finally, if skin blisters or rashes occur while taking this medication, the patient should inform their doctor immediately and receive proper diagnosis and treatment.

Serious side effects

Urticaria, angioedema, blistering and exfoliative skin lesions, hepatitis (liver dysfunction), acute pancreatitis, severe and disabling joint pain, bullous pemphigoid, lactic acidosis, severe edema accompanied by increased blood pressure, jaundice, severe allergic reaction, liver abnormalities (jaundice), severe skin adverse reactions

Mild side effects

• Tremor
• headache
• dizziness
• fatigue
• nausea
• gastroesophageal reflux
• diarrhea
• bloating
• weakness
• excessive sweating

This medication should be stored in a sealed container to prevent air and moisture ingress and kept in a cool place at or below 30 degrees Celsius to maintain its effectiveness.

Appearance

Bright yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle