Empagliflozin/Metformin Hydrochloride Duo Tablet 12.5/850 mg

Adult dose

The recommended dose of this medication is 1 tablet, twice a day. It is determined based on the current treatment regimen, efficacy, and tolerability of each patient, not exceeding 25 mg of empagliflozin and 2000 mg of metformin. For patients for whom adequate blood sugar control cannot be achieved with metformin alone or using other drugs such as insulin, the recommended dosage is 5 mg of empagliflozin twice daily (10 mg total per day).

This medication is an anti-diabetic treatment that helps lower blood sugar, with the two components working together to aid in blood sugar control. Before use, renal function must be checked to ensure it is normal, and it should not be used in cases of severe renal impairment. Patients in acute conditions such as severe infections, dehydration, heart problems, or acute myocardial infarction should also avoid taking this medication. This medication is not to be administered to women who are pregnant or might become pregnant, or to breastfeeding mothers. This medication can cause hypoglycemia, so caution is advised regarding symptoms of low blood sugar when used with insulin or other blood glucose-lowering agents, and dosage adjustments may be necessary. Lactic acidosis, a serious side effect, can rarely occur, so if symptoms such as malaise, muscle pain, shortness of breath, or abdominal pain arise, it is essential to consult a doctor immediately. Additionally, urinary or genital infections may occur, so quick treatment is necessary if infection symptoms appear. In situations where there is concern about fluid loss or dehydration, blood pressure and hydration status should be monitored closely, particularly in the elderly or patients with cardiovascular disease. This medication should be discontinued for a period before and after undergoing surgery, and should also be temporarily stopped when receiving iodinated contrast tests. This medication may lower vitamin B12 levels, so regular blood tests are recommended. In case of overdose, there is a risk of lactic acidosis, and immediate medical treatment should be sought, as blood dialysis may be necessary. Safety and efficacy in children and adolescents under the age of 18 have not been established, so it is not recommended for this group. It is advisable to avoid alcohol consumption while taking this medication, and while no specific effects have been reported regarding driving or operating machinery, caution is still advised. This medication must be taken strictly under a physician's prescription and guidance, and any unusual symptoms should prompt an immediate consultation with a healthcare professional.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, severe rashes with high fever, blisters, skin peeling, oral/ocular mucosal pain, severe dermatological reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, breathing problems, jaundice (yellowing of skin or eyes), extreme lethargy, liver dysfunction (jaundice), sudden and severe

Mild side effects

• Urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation
• abnormal liver function tests

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be kept at room temperature between 1 to 30 degrees Celsius. Proper storage will maintain the medication's efficacy and safety.

Appearance

Biconvex oval film-coated tablet, white with a pink hue

Package unit

10 tablets/box [10 tablets/PTP x 1], 60 tablets/box [10 tablets/PTP x 6], 30 tablets/bottle, 60 tablets/bottle