Selecaduo Tablet

Adult dose

Adults: Take 1 tablet twice daily. This medicine may be taken with or without food. Take this medicine whole; do not crush or split it. ○ Patients with hepatic impairment This medicine is not recommended for initial treatment in patients with hepatic impairment who require a dose reduction (see Precautions for Use, 5. General Precautions)

This medication may pose a risk of gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic beverages daily, and consultation with a physician or pharmacist is essential. It can affect the cardiovascular system and may increase the risk of serious thrombotic events such as myocardial infarction or stroke. Therefore, it should be taken at the lowest effective dose for the shortest duration, with careful monitoring for cardiovascular symptoms. There is a risk of gastrointestinal issues such as ulcers, bleeding, and perforation, especially in elderly patients and those with a history of gastrointestinal diseases. Symptoms such as epigastric pain, dyspepsia, hematemesis, and melena warrant immediate medical attention. This drug is contraindicated for patients with specific allergic reactions, severe heart, liver or kidney diseases, inflammatory bowel diseases, pregnant or nursing women, and those with certain genetic lactose intolerance. Patients with impaired kidney or liver functions, as well as those with asthma, hypertension, or heart failure, require careful monitoring during use. Adverse reactions may occur during use, such as headache, dyspepsia, swelling, skin rashes, and dizziness. If these symptoms persist or worsen, consultation with a physician is advised. As this drug is metabolized in the liver, dose adjustment may be necessary for individuals with compromised liver function or those taking specific medications concurrently. Women who are pregnant or could become pregnant should not take this medication, and if pregnancy occurs during treatment, it should be discontinued immediately. Elderly patients may be at a greater risk for impaired kidney, liver, or heart function and should use this medication with extra caution, with regular testing recommended. Dizziness and drowsiness may occur, so driving or operating machinery should be avoided. Long-term use of this medication requires regular blood tests and monitoring of liver and kidney functions, with cessation required if abnormal findings occur. Overdosage may result in symptoms such as vomiting, lethargy, drowsiness, and gastrointestinal bleeding, necessitating immediate medical attention for appropriate care. Keep this medication out of the reach of children and avoid transferring it to other containers.

Gastrointestinal bleeding, cardiovascular thrombotic response, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, dyspepsia, nausea, upper abdominal pain, constipation, diarrhea, dry mouth, esophageal pain, stomatitis, COVID-19, acute pyelonephritis, facial swelling, pain at the site of insertion, peripheral edema, fever, pruritus, psoriasis, rash, skin swelling, elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated blood pressure, elevated blood uric acid, elevated gamma-glutamyl transpeptidase, arthralgia, low back pain, coccygodynia, flank pain, headache, carpal tunnel syndrome, lymphadenopathy, cholelithiasis, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, hives, angioedema, alopecia, blistering dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, vasculitis, contact dermatitis, skin nodules, taste disturbance, albuminuria, cystitis, hematuria, dysuria, pollakiuria, nephrolithiasis, urinary incontinence, visual disturbance, cataract, conjunctivitis, ocular pain, glaucoma, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive hematuria, positive proteinuria, renal dysfunction, acute renal failure, interstitial nephritis, heartburn, weakness, hypertriglyceridemia, hypercholesterolemia, transaminitis, increased ALT, increased AST, leukopenia, chest discomfort, blurred vision, gastritis, gastroesophageal reflux, headache, dizziness, drowsiness, allergic reaction, asthenia, chest pain, fluid retention, generalized edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, angioedema, hallucinations, exacerbation of epilepsy, bronchospasm, exacerbation of bronchospasm, dyspnea, laryngitis, pneumonia, epistaxis, dysphonia, vesicular dermatitis, petechial hemorrhage, dermatitis, nail disorders, photosensitivity reaction, erythematous rash, maculopapular rash, skin dryness, hyperhidrosis, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, drug rash, arrhythmia, left ventricular hypertrophy, angina, unstable angina, coronary artery disorders, myocardial infarction, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, homonymous hemianopia, syncope, ventricular tachycardia, pulmonary embolism, cerebrovascular accident, peripheral necrosis, thrombophlebitis, vasculitis, deep vein thrombosis, cerebral hemorrhage, solitary lesion, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, elevated sodium levels, elevated potassium levels, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, elevated NPN, increased creatinine, elevated alkaline phosphatase, weight gain, decreased appetite, increased LDH, hypoglycemia, hyponatremia, synovial cyst, arthrosis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in the back, muscle stiffness, decreased hematocrit, increased hemoglobin, petechial hemorrhage, epistaxis, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, vasculitis, contact dermatitis, skin nodules, taste disturbance, albuminuria, cystitis, hematuria, dysuria, pollakiuria, nephrolithiasis, urinary incontinence, visual disturbance, cataract, conjunctivitis, ocular pain, glaucoma, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive hematuria, positive proteinuria, renal dysfunction, acute renal failure, interstitial nephritis, heartburn, weakness, hypertriglyceridemia, hypercholesterolemia, transaminitis, increased ALT, increased AST, leukopenia, chest discomfort, blurred vision, gastritis, gastroesophageal reflux, headache, dizziness, drowsiness, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, bile stasis, bile duct stasis hepatitis, jaundice, photosensitive reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, menstrual disorders, female infertility, chest pain, heartburn, dyspepsia, dry mouth, nausea, diarrhea, facial swelling, generalized edema, weakness, itching, leukopenia, neutropenia, chest discomfort, headache, upper respiratory tract infection, blurred vision, hives, anemia, thirst, ulcerative stomatitis, gastritis, allergy, low back pain, chest pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive RA factor, herpes zoster, pneumonia, dyspnea, increased ALT, hearing impairment, constipation, gastric ulcer, anemia, insomnia

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. It is recommended to maintain a storage temperature between 1°C and 30°C at room temperature to preserve the effectiveness and safety of the drug.

Appearance

Yellow rectangular film-coated tablet consisting of two layers

Package unit

30 tablets/bottle, 300 tablets/bottle