Sereduo Tablet

Adult dose

Adults: Take 1 tablet twice daily. This medicine may be taken with or without food. Take this medicine whole; do not crush or split it. ○ Patients with hepatic impairment This medicine is not recommended for initial treatment in patients with hepatic impairment who require a dose reduction (see Precautions for Use, 5. General Precautions)

This medication may pose a risk of gastrointestinal bleeding for individuals who regularly consume more than three alcoholic beverages daily, so consultation with a doctor or pharmacist is essential. This drug may increase the risk of cardiovascular thrombotic events such as myocardial infarction and stroke, thus it should be used at the lowest effective dose for the shortest duration possible, with careful monitoring for cardiovascular symptoms. Serious adverse reactions such as ulcers, bleeding, or perforation in the gastrointestinal tract may occur, so particularly those with a history of gastrointestinal disorders or the elderly should exercise caution and seek immediate treatment if gastrointestinal bleeding symptoms arise. Individuals with a history of allergy to this medication, as well as those with asthma, cardiovascular diseases, severe liver or kidney conditions, active peptic ulcers, inflammatory bowel diseases, pregnant or nursing women, should not take this medication. Patients with impaired liver or kidney function, hypertension, heart failure, edema, and the elderly should use this medication cautiously, with regular monitoring and investigations as necessary. During the use of this medication, it is important to routinely check liver function, kidney function, and blood tests to ensure there are no abnormal signs. This medication can interact with other drugs; thus, consultation with a doctor is recommended, especially for drugs metabolized by the liver, anticoagulants, diuretics, and antihypertensives. Pregnant women or those who may become pregnant should avoid this medication, and if pregnancy is confirmed during treatment, it should be discontinued immediately. Lactating women should consult a physician regarding the use of this medication during breastfeeding and may need to discontinue breastfeeding. The safety and efficacy of this medication have not been established in children and adolescents; therefore, it is advisable not to use it in individuals under 18. Dizziness or drowsiness may occur during treatment; caution should be taken when driving or operating machinery. If any unusual symptoms such as skin rash, fever, or mucosal lesions occur during treatment, discontinue use immediately and consult a physician. In case of overdose, symptoms such as nausea, vomiting, lethargy, and gastrointestinal bleeding may present; seek medical attention immediately as there is no specific antidote. Keep out of reach of children, and do not transfer to another container for safety.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforations, ulcers, bleeding, dyspepsia, nausea, abdominal pain, constipation, diarrhea, dry mouth, esophageal pain, stomatitis, COVID-19, acute pyelonephritis, facial swelling, pain at the insertion site, peripheral edema, fever, pruritus, psoriasis, rash, skin swelling, elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated blood pressure, increased serum uric acid, elevated gamma-glutamyltransferase, arthralgia, lower back pain, coccygodynia, flank pain, headache, carpal tunnel syndrome, lymphadenopathy, cholelithiasis, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, distension, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, urticaria, angioedema, alopecia, blistering dermatitis, peripheral edema, facial swelling, influenza-like illness, damage, insomnia, anxiety, confused state, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, gastritis, gastroesophageal reflux, exacerbation of gastrointestinal inflammation, angular cheilitis, intestinal obstruction, bowel perforation, gastrointestinal bleeding, hemorrhagic colitis, esophageal perforation, intestinal obstruction, alveolar osteitis after tooth extraction, bowel anastomosis ulcer, melena, glossitis, aphthous stomatitis, oral mucosa vesiculation, numbness of the mouth, oral pain, leg cramps, hypertonicity, sensory decrease, migraine, neuralgia, neuropathy, dysesthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, back pain, allergy exacerbation, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, angioedema, chest pain, anorexia, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infection, sinusitis, pharyngitis, rhinitis, bronchitis, bronchospasm, exacerbation of bronchospasm, dyspnea, laryngitis, pneumonia, epistaxis, voice disorders, vesicular dermatitis, purpura, dermatitis, nail disease, photosensitive reactions, pruritus, erythematous rash, maculopapular lesions, skin disorders, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, mucocutaneous syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug eruption accompanied by eosinophilia and systemic symptoms, peripheral edema, facial swelling, influenza-like illness, damage, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, vasculitis, contact dermatitis, injection site reactions, skin nodules, dysgeusia, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, heartburn, weakness, hypertriglyceridemia, hypercholesterolemia, transaminitis, elevated ALT, elevated AST, itching, leukopenia, neutropenia, chest discomfort, blurred vision, epigastric discomfort, gastritis, urticaria, thirst, abdominal pain, gastroesophageal reflux.

This medication can be sensitive to air and moisture; therefore, it should be stored in a tightly sealed container. It is best to maintain storage temperatures between 1 to 30 degrees Celsius. This will help preserve the drug's efficacy over time.

Appearance

Yellow, oblong film-coated tablet consisting of two layers

Package unit

30 tablets/bottle, 300 tablets/bottle