Bonecox Tablet

Adult dose

Adults: Take 1 tablet twice daily. This medicine may be taken with or without food. Take this medicine whole; do not crush or split it. ○ Patients with hepatic impairment This medicine is not recommended for initial treatment in patients with hepatic impairment who require a dose reduction (see Precautions for Use, 5. General Precautions)

This medication should be discussed with a doctor or pharmacist before use by individuals who regularly consume more than three drinks of alcohol daily, as it can cause gastric bleeding. Additionally, this medication may increase the risk of cardiovascular thrombotic events such as myocardial infarction or stroke, so those with a history of cardiovascular disease or risk factors should exercise particular caution. It is important to use the minimum effective dose for the shortest period possible and to consult medical personnel immediately if cardiovascular symptoms occur. This medication can cause serious side effects such as ulcers, bleeding, or perforations in the gastrointestinal tract; therefore, caution should be taken by those with a history of gastrointestinal diseases or the elderly. If symptoms such as epigastric pain, dyspepsia, black stools, or vomiting of blood occur, it should be reported to medical personnel immediately. This medication is not to be administered to those with specific allergic reactions, severe asthma, cardiovascular, liver, or kidney diseases, active gastric ulcers, inflammatory bowel disease, pregnant or nursing women, or individuals with lactose intolerance. Those with compromised liver or kidney function, hypertension, heart failure, asthma patients, the elderly, and diabetes patients should use this medication with increased caution, and regular check-ups should be carried out to monitor for abnormalities. During use, side effects such as headaches, dyspepsia, diarrhea, rashes, swelling, hypertension, and dizziness may occur, and in severe cases, immediate cessation of use and consultation with medical personnel is necessary. This medication is metabolized in the liver, so if taken with specific medications, blood concentration may change, necessitating dosage adjustment. Pregnant women or those planning to become pregnant should avoid taking it, and breastfeeding women should consult professionals before taking it. The safety of this medication in children and adolescents has not been established, so it is better not to use it. The elderly may have decreased kidney, liver, and heart functions, so increased caution is needed when taking it, and it is advisable to start with the minimum dose if the individual weighs less. Those taking this medication for an extended period should undergo regular blood tests and liver and kidney function tests to check for abnormalities. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and abdominal pain may arise, and immediate medical assistance is required. This medication must be kept out of the reach of children, and care should be taken not to transfer it to other containers, as this may cause accidents.

Gastrointestinal bleeding, cardiovascular thromboembolic events, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcer, bleeding, dyspepsia, nausea, upper abdominal pain, constipation, diarrhea, dry mouth, esophageal pain, stomatitis, COVID-19, acute pyelonephritis, facial swelling, pain at the injection site, peripheral edema, fever, pruritus, psoriasis, rash, skin swelling, increased alanine aminotransferase, increased aspartate aminotransferase, increased blood pressure, increased serum uric acid, increased gamma-glutamyl transferase, arthralgia, back pain, coccygodynia, flank pain, headache, carpal tunnel syndrome, lymphadenopathy, cholelithiasis, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, influenza-like illness, injury, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, gastrointestinal bleeding, liver enzyme elevation, bullous dermatitis, angioedema, alopecia, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, eosinophilic inflammation, contact dermatitis, injection site reactions, skin nodules, taste disturbances, albuminuria, cystitis, hematuria, dysuria, increased frequency of urination, nephrolithiasis, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased N-acetyl-β-D-glucosaminidase, positive urinary hematuria, positive urinary protein, renal impairment, acute renal failure, interstitial nephritis, heartburn, weakness, hypertriglyceridemia, hypercholesterolemia, transaminitis, increased ALT, increased AST, leukopenia, neutropenia, chest discomfort, blurred vision, menstrual disorder, breast tenderness, menopausal symptoms, fibrocystic breast disease, chest neoplasm, chest pain, dysmenorrhea, menstrual disorder, vaginal bleeding, vaginitis, prostate disorder, ovarian cyst, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased non-protein nitrogen, increased creatinine, increased alkaline phosphatase, weight gain, anorexia, increased LDH, hypoglycemia, hyponatremia, bursitis, arthrosis, skeletal malformation, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fracture, tendon rupture, pain in extremities, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopenia, anemia, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, skin nodules, taste disturbances, allergic reaction, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, angioedema, hallucinations, exacerbation of epilepsy, upper respiratory infection, sinusitis, pharyngitis, rhinitis, bronchitis, bronchial spasm, exacerbated bronchial spasm, dyspnea, laryngitis, pneumonia, epistaxis, vocal cord dysfunction, bullous dermatitis, petechiae, alopecia, dermatitis, nail disease, photosensitivity reaction, pruritus, erythematous rash, maculopapular rash, skin disease, dry skin, increased sweating, polymorphous light eruption, exfoliative dermatitis, mucocutaneous syndrome, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, injury, chest pain, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, polymorphous light eruption, toxic epidermal necrolysis, drug rash, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, female infertility, chest pain, heartburn, xerostomia, nausea, diarrhea, facial edema, generalized edema, weakness, hypertriglyceridemia, hypercholesterolemia, transaminitis, increased ALT, increased AST, itching, leukopenia, neutropenia, chest discomfort, headache, upper respiratory infection, blurred vision, headache, dizziness, drowsiness, gastritis, gastroesophageal reflux, peripheral edema, gastrointestinal bleeding, acute renal failure, hypertension, acute renal failure, respiratory depression, coma, vomiting, lethargy, drowsiness

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. The recommended storage temperature is room temperature between 1 to 30 degrees Celsius. By storing it this way, the efficacy and safety of the medication can be maintained for a long time.

Appearance

Yellow oblong film-coated tablets consisting of two layers

Package unit

30 tablets per bottle, 300 tablets per bottle