Medication info
Sitadyon Tablet 100/15 mg (Sitagliptin Phosphate Hydrate, Pioglitazone Hydrochloride)

Sitadyon Tablet 100/15 mg (Sitagliptin Phosphate Hydrate, Pioglitazone Hydrochloride)

Prescription medicationTablet
Ingredient · strength
Sitagliptin Phosphate Hydrate›128.5mg / 1 tabletPioglitazone Hydrochloride›16.53mg / 1 tablet
Manufacturer / importer
(주)마더스제약
Appearance
Pink oval film-coated tablet
Packaging
Bottle packaging - 30 tablets/bottle, Bottle packaging - 100 tablets/bottle
Approval status
Active

MFDS item code 202302365 · Approved 2023.08.08 · Insurance code 622805100

Summary

Main use
Improvement of blood glucose control in type 2 diabetes
Who uses it
Adults
Adult dosage
This medication can be administered to patients with type 2 diabetes who are taking sitagliptin 100 mg and pioglitazone 15 mg or 30 mg, at a dose of one tablet per day regardless of meals.

Ingredients

Manufacturer
(주)마더스제약

Efficacy & effects

Improvement of blood glucose control in type 2 diabetes

View approved original text

This medication helps improve blood glucose control in patients with type 2 diabetes through the combination of sitagliptin and pioglitazone. It is effectively used as an adjunct to dietary and exercise therapy for blood glucose management. This contributes to a stable improvement in blood glucose levels for diabetes management.

Dosage and Administration

Adult dosage

This medication can be administered to patients with type 2 diabetes who are taking sitagliptin 100 mg and pioglitazone 15 mg or 30 mg, at a dose of one tablet per day regardless of meals.

Precautions

This medication may cause serious allergic reactions in some patients, so if symptoms such as rash, swelling, or difficulty breathing occur during treatment, it should be discontinued immediately and a physician consulted. This medication can cause pancreatitis, so if symptoms such as abdominal pain, nausea, vomiting, or loss of appetite arise during use, immediate medical attention is required. One of the components of this medication may affect heart function, therefore, patients with heart failure or a history of heart failure should not take this medicine. Patients at risk of heart failure should carefully monitor for signs such as weight gain, shortness of breath, or leg swelling while taking this medication, and should inform medical personnel if any abnormal symptoms appear. Dose adjustments are necessary for patients with reduced kidney function, and this medication should be avoided in cases of severe kidney impairment. Women who are pregnant or may become pregnant should avoid taking this medication, and premenopausal women should use appropriate contraception while taking it. This medication is contraindicated in patients with a history of bladder cancer or active bladder cancer, and such patients should not take it. Patients should report any signs of liver dysfunction, such as fatigue, loss of appetite, or jaundice to medical personnel immediately, and regular liver function tests are recommended. This medication can cause hypoglycemia, so particular care should be taken for symptoms of hypoglycemia, especially when taken with insulin or sulfonylureas, and blood glucose levels should be checked frequently. This medication can cause weight gain and edema, so periodic monitoring of weight changes is necessary, and if edema worsens, a consultation with a physician is recommended. Additionally, if severe muscle pain or joint pain occurs during treatment, patients should inform their doctor, and if blisters or rashes appear on the skin, immediate medical attention should be sought. This medication may interact with other drugs, so if other medications are being taken, it is essential to inform medical personnel, and do not discontinue or alter medication usage without consulting them.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, anaphylaxis, angioedema, Stevens-Johnson syndrome, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, acute pancreatitis, difficulty breathing or shortness of breath, asthma attacks, respiratory disturbances with cough + fever, yellowing of the skin or eyes (jaundice), profound malaise throughout the body, sudden and very severe headache

Mild side effects

  • Upper respiratory tract infection
  • nasopharyngitis
  • headache
  • diarrhea
  • nausea
  • constipation
  • abdominal bloating
  • muscle pain
  • limb pain
  • back pain
Show 26 more
  • pruritus
  • thrombocytopenia
  • hypoglycemia
  • indigestion
  • dizziness
  • weight gain
  • increase in blood glucose
  • dizziness
  • loss of appetite
  • vomiting
  • itching
  • tremors
  • chills
  • discomfort in the epigastric region
  • numbness
  • muscle stiffness
  • discomfort in the head
  • increased liver enzymes
  • worsening of liver disease
  • eczema
  • joint pain
  • knee abnormalities
  • arm weakness
  • proteinuria
  • increased blood creatinine
  • anxiety

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to keep air out, and it is best to store it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication.

Appearance and packaging

Appearance

Pink oval film-coated tablet

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.