Piobria Tablets 100/15 mg (Sitagliptin Phosphate Hydrate, Pioglitazone Hydrochloride)

Adult dosage

This medication can be administered to patients with type 2 diabetes receiving sitagliptin 100 mg and pioglitazone 15 mg or 30 mg, one tablet once a day regardless of meals.

This medication consists of sitagliptin and pioglitazone components and is used for the treatment of diabetes. First, the sitagliptin component can rarely cause serious allergic reactions; thus, if symptoms such as skin rashes, difficulty breathing, or swelling of the face or neck occur after taking the medication, you must stop taking it immediately and consult a doctor. Additionally, sitagliptin may pose a risk of acute pancreatitis, which is inflammation of the pancreas, so if symptoms such as abdominal pain, vomiting, or fever develop while taking it, you should consult your healthcare provider immediately. The pioglitazone component may cause or exacerbate edema or heart failure in patients with weak heart function, so patients with a history or symptoms of heart failure should not use this medication. Moreover, during treatment with this medication, if you experience weight changes, difficulty breathing, or leg swelling, you should inform your doctor right away. Caution is needed for patients with impaired kidney function, who should have regular kidney function tests; those with severe renal impairment should avoid using this medication. It is recommended that this medication not be used in patients with active bladder cancer or a history of bladder cancer. Women who are pregnant or may become pregnant must consult a doctor before taking this medication. While taking this medication, symptoms of hypoglycemia (dizziness, headaches, trembling, etc.) may occur, so you should check your blood sugar immediately when symptoms appear and take appropriate measures if necessary. This medication may cause weight gain and edema, so regular monitoring of weight is advisable, and if symptoms of edema occur, please consult a doctor. Furthermore, this medication can potentially cause abnormalities in liver function; therefore, liver function tests should be performed before and during treatment, and if symptoms of liver damage (fatigue, loss of appetite, jaundice, etc.) occur, notify your doctor immediately. This medication may interact with other drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist and seek advice. Finally, if any unusual symptoms occur while taking this medication, please consult your healthcare provider immediately for appropriate measures.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, rash, blisters, peeling skin, mucosal pain in the mouth/eyes, jaundice, severe general fatigue, sudden severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, significantly decreased urine output, severe generalized swelling and increased blood pressure, anaphylaxis, angioedema, Stevens-Johnson syndrome, acute pancreatitis, acute

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• headache
• muscle pain
• limb pain
• back pain
• constipation
• vomiting
• dyspepsia
• dizziness

This medication should be stored in a tightly closed container to prevent air entry and kept at room temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the medication's effectiveness and prevent degradation.

Appearance

Pink oval film-coated tablet

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 100 tablets/bottle