Piobiar Tablet 100/30 mg (Sitagliptin Phosphate Hydrate, Pioglitazone Hydrochloride)

Adult dosage

This medication may be administered once daily at a dose of one tablet for patients with type 2 diabetes, combining 100 mg of sitagliptin and 15 mg or 30 mg of pioglitazone, regardless of meal timing.

This medication contains sitagliptin and pioglitazone and is used for diabetes treatment. Sitagliptin can rarely cause serious allergic reactions. Therefore, if symptoms such as rash, difficulty breathing, or swelling of the face or tongue occur within three months of administration, the medication should be discontinued immediately and medical consultation should be sought. Additionally, sitagliptin may cause acute pancreatitis, so if symptoms like upper abdominal pain, vomiting, or loss of appetite occur, medical attention should be sought immediately. Pioglitazone may cause fluid retention, exacerbating heart failure, so patients with heart failure or a history of heart failure should not take this medication. When taking pioglitazone, watch for symptoms of swelling or shortness of breath, and consult a doctor if these symptoms occur. This medication should not be administered to patients with bladder cancer or a history of bladder cancer, and immediate medical attention should be sought if gross hematuria or urination issues arise. Patients with severely impaired kidney or liver function must consult a doctor before taking this medication, and dosage adjustment may be necessary if kidney function is decreased. It is safest for women who are pregnant or could become pregnant to avoid taking this medication. While taking this medication, signs of hypoglycemia (dizziness, cold sweat, severe fatigue, etc.) may occur, so caution is advised, especially when taken with other diabetes medications. Furthermore, this medication may cause side effects such as headache, upper respiratory tract infections, edema, weight gain, dyspepsia, etc. Therefore, if any unusual symptoms persist, medical consultation should be sought. Prior to taking this medication, it is essential to inform the doctor of your medical history and any medications currently being taken, and to regularly undergo blood tests and liver function tests.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/conjunctival mucosa, severe allergic reactions, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough + fever, breathing problems, jaundice (yellowing of skin or eyes), extreme lethargy, liver abnormalities (jaundice), sudden onset of

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• headache
• diarrhea
• nausea
• constipation
• muscle pain
• limb pain
• back pain
• pruritus

This medication should be stored in a tightly-closed container to prevent air and moisture from entering, at a temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the drug's effectiveness for longer periods.

Appearance

Yellow oval film-coated tablet

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 100 tablets/bottle