Zabiam 50/850 mg (Sitagliptin Hydrate, Metformin Hydrochloride)

Adult dose

This medication is generally taken twice daily with food. To reduce gastrointestinal side effects caused by Metformin, the dosage should be increased gradually. 1. Patients not currently treated with Metformin: This medication 50/500 mg is to be taken twice daily, with 1 tablet at a time, and can be increased to 50/1000 mg taken twice daily, with 1 tablet each time. 2. Patients currently treated with Metformin:

This medication is used for the treatment of diabetes and helps in managing blood sugar levels. During usage, severe allergic reactions may occur; if symptoms such as skin rash or difficulty breathing emerge, discontinue use immediately and consult a doctor. Additionally, there is a risk of pancreatitis (inflammation of the pancreas), so if you experience abdominal pain, vomiting, or persistent abdominal discomfort, inform your healthcare provider promptly. This medication contains ingredients that can affect kidney function, and patients with severely impaired kidney function should not take it. In particular, avoid using this medication in cases of dehydration, severe infection, or sudden worsening of heart function, and discontinue use for a period before and after surgery. Women who are pregnant or breastfeeding should refrain from using this medication for safety. During the use of this medication, regular blood tests and kidney function tests should be conducted to monitor your health status. Moreover, when used in conjunction with other blood sugar lowering agents, hypoglycemia symptoms may occur, so it is important to be cautious and respond immediately if symptoms appear. Alcohol consumption may pose risks when taken with this medication, so it is advisable to avoid alcohol during treatment. When performing tasks requiring attention, such as driving or operating machinery, be cautious for hypoglycemia or dizziness. Rarely, severe joint pain or skin conditions may occur; if these symptoms develop, inform your doctor. During treatment, maintaining a healthy diet and regular exercise, along with regularly checking blood sugar and kidney function, is important.

Serious side effects

Urticaria, severe swelling (edema), anaphylaxis, angioedema, exfoliative skin diseases (including Stevens-Johnson syndrome), acute pancreatitis, acute renal failure, dyspnea, unstable angina, severe hypoglycemia, acute renal failure, blistering dermatitis, severe and disabling joint pain, jaundice (yellowing of the skin or eyes), lactic acidosis, severe edema, hypertension, severe allergic reactions, severe neurological symptoms (e.g., severe

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infection
• nasopharyngitis
• headache
• muscle pain
• limb pain
• back pain

Store this medication in a tightly closed container to prevent air exposure, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the efficacy and safety of the medication.

Appearance

Pink oval film-coated tablet

Package unit

60 tablets/box [10 T/PTP*6]