Benamet Extended-Release Tablet 0.3/1000 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

This medication is administered as one tablet once daily with meals to patients receiving 0.3 mg of empagliflozin and 1000 mg of extended-release metformin hydrochloride.

This medicine contains two components: metformin hydrochloride and empagliflozin. Metformin hydrochloride helps lower blood sugar levels, but in rare cases, it can cause a serious side effect called lactic acidosis. Lactic acidosis is a condition that occurs when there is an excessive accumulation of lactic acid in the body and can manifest symptoms such as difficulty breathing, abdominal pain, and fatigue, and if untreated, can be life-threatening. There is also a risk of hypoglycemia when taking this medication, especially if meals are skipped or irregular, excessive exercise occurs, or alcohol is consumed. This medication should not be used in cases of poor kidney function or acute conditions that may affect kidney function, such as dehydration, severe infection, heart failure, acute myocardial infarction, or sepsis. Additionally, empagliflozin, one of the components of this medication, acts by promoting the excretion of glucose through urine, which can lead to urinary tract infections or genital infections. If symptoms of infection occur, consultation with a healthcare professional should be sought immediately. If surgery is planned or if tests involving iodinated contrast agents are to be conducted, administration should be temporarily discontinued, and dosing should resume only after normal kidney function has been confirmed following surgery or examination. This medication is not recommended during pregnancy or breastfeeding. Elderly patients or those with reduced kidney function should have dosages adjusted and kidney function monitored regularly. During treatment, adequate hydration is necessary to prevent symptoms of dehydration or hypotension, and any sudden weight loss should be reported to a healthcare provider. This medication should be swallowed whole and not crushed or chewed, and while the tablet shell may appear in the stool, this is normal. It is advisable to avoid alcohol consumption while taking this medication, and caution should be exercised when combined with other blood sugar-lowering agents as this may increase the risk of hypoglycemia. If an overdose occurs, medical attention should be sought immediately, especially if symptoms of lactic acidosis are suspected.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blistering skin, painful mucous membranes of the mouth/eyes, difficulty breathing or breathlessness, asthma attacks, respiratory issues accompanied by coughing and fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headaches, lightning headaches, seizures, confusion, visual disturbances, paralysis, decreased urine output

Mild side effects

• Dyspepsia
• constipation
• gastritis
• upper abdominal pain
• abdominal pain
• diarrhea
• dry mouth
• enterocolitis
• bloody stools
• parotitis

This medication should be stored in a sealed container to prevent exposure to air or moisture. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius.

Appearance

An oval extended-release bicolored tablet, white and light pink

Package unit

30 tablets/bottle, 300 tablets/bottle, 28 tablets/box [(7 tablets/PTP) X 4]