Glimemajac Tablet 50/1000 mg (Sitagliptin, Metformin)

Adult dose

The usual dosage of this medication is 1 tablet taken twice daily with meals. To reduce gastrointestinal adverse reactions caused by metformin, the dosage should be gradually increased. 1. For patients who are currently not treated with metformin: - Start with an initial dose of this medication 50/500 mg, 1 tablet twice daily. - If necessary, the dose may be increased to this medication 50/1000 mg, 1 tablet twice daily. 2.

This medication contains two ingredients that help control blood sugar levels. First, one of this medication's components may cause allergic reactions, so if symptoms such as skin rash, hives, or severe cases such as breathing difficulties occur, it is essential to stop taking the medication immediately and consult a physician. Additionally, this component has been reported to potentially cause a serious side effect known as pancreatitis, characterized by inflammation of the pancreas; therefore, if symptoms like abdominal pain or vomiting occur during use, careful observation is required and discontinuation may be necessary. The other component should not be administered to patients with weakened kidney function or those in states that could affect kidney function, such as dehydration, severe infections, heart failure, or acute myocardial infarction. Furthermore, this medication is not recommended for pregnant women, women who may become pregnant, lactating women, or children under 18 years old. During the use of this medication, kidney function should be regularly monitored, and if kidney function declines, the medication should be discontinued. This medication may cause hypoglycemia; therefore, especially when taken with other blood sugar-lowering medications, it is important to frequently check blood sugar levels and be alert for symptoms of hypoglycemia. Additionally, a rare but serious metabolic disorder known as lactic acidosis may occur, so if sudden fatigue, muscle pain, difficulty breathing, or abdominal pain manifests, it is crucial to notify a physician immediately. It is advisable to avoid alcohol consumption while taking this medication, and if a surgery is approaching or tests using iodinated contrast agents are planned, temporary discontinuation of the medication should be considered. Maintaining regular meals and appropriate exercise is important during medication use, and any abnormal symptoms should be reported to healthcare professionals promptly. Lastly, this medication may interact with certain other drugs, so if other medications are being taken concurrently, it is essential to inform healthcare professionals.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, severe allergic reactions, rash, vascularitis, Stevens-Johnson syndrome, exfoliative skin disease, acute pancreatitis (including hemorrhagic or necrotizing), acute renal failure, difficulty breathing, severe and debilitating joint pain, bullous pemphigoid, jaundice (yellowing of the skin or eyes), severe hypoglycemia, lactic acidosis, acute or chronic metabolic acidosis (including ketoacidosis)

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory tract infection
• nasopharyngitis
• headache
• muscle pain
• limb pain
• back pain

This medication should be stored in a sealed container to prevent air exposure and kept at room temperature between 1 and 30 degrees Celsius. This storage condition helps maintain the effectiveness of the medication.

Appearance

Brown oval film-coated tablet

Package unit

60 tablets/box [10 tablets/PTP x 6]