Januglu Tablets 100 Milligrams (Sitagliptin Hydrochloride Hydrate)

Adult dosage

This medication is administered as 100 mg once daily for monotherapy or combination therapy, with a maximum daily dose of 100 mg. This medication can be taken regardless of meals. In patients with renal impairment, dosage adjustments are necessary based on kidney function. - Mild renal impairment (eGFR 60 to <90): No dosage adjustment is needed. - Moderate renal impairment (eGFR 45 to <60): Dosage adjustment required.

This medication may cause severe allergic reactions after administration; therefore, if symptoms of allergy or skin abnormalities appear, it should be discontinued immediately, and a physician should be consulted. Acute pancreatitis symptoms may occur, so if symptoms such as abdominal pain or vomiting arise, it is important to promptly inform healthcare personnel. It should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor in case of allergy to this medication or any of its components. Patients with impaired renal function should have their dosage adjusted, and they should take the medication following kidney function tests and the physician’s guidance. During treatment with this medication, symptoms similar to a cold, headaches, gastrointestinal symptoms, etc., may occur, so caution is needed. When taken with insulin or sulfonylureas, the risk of hypoglycemia may increase; therefore, regular checks of blood sugar levels and adjustments to medication dosage should be carried out as necessary. Severe joint pain or the appearance of skin blisters may be side effects of this medication, and prompt communication with a doctor is required; if symptoms are severe, discontinuation of the medication may be necessary. Pregnant or breastfeeding women are advised not to take this medication; there is insufficient evidence of safety and efficacy in children, so caution is warranted in their use. In cases of overdose, immediate medical attention is needed, and this medication can be partially removed by hemodialysis. It is important to regularly monitor kidney function and blood sugar levels while taking this medication, and consult with a physician regarding potential interactions with other medications.

Serious side effects

• Hives
• angioedema
• anaphylaxis
• Stevens-Johnson syndrome
• exfoliative skin disease
• severe skin adverse reactions
• acute pancreatitis
• elevated liver enzymes
• acute renal failure
• severe and disabling joint pain

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly closed container to prevent air and moisture from entering, and it is best kept at room temperature between 1 and 30 degrees Celsius. By maintaining proper temperature and environment, the effectiveness of the medication can be preserved.

Appearance

Bright yellow-orange round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle