Dap Duo Extended Release Tablets 10/500 mg

Adult dose

This medication is typically administered once daily with the evening meal. The maximum dosage is once daily dapagliflozin 10 mg/extended-release metformin 2000 mg. For initial therapy, the recommended starting dose is one tablet of 5 mg/500 mg or 10 mg/500 mg once daily. The dosage should be gradually adjusted to minimize gastrointestinal side effects associated with metformin. This medication must be swallowed whole and not crushed.

This medication is used in the treatment of diabetes and aids in the control of blood sugar. However, it should not be administered to patients with reduced kidney function, severe infections, or dehydration. Additionally, it is advisable for women who are pregnant or nursing to avoid using this medication. Rarely, this medication may cause lactic acidosis, a dangerous condition, so consult a doctor immediately if symptoms occur. Hypoglycemia may occur when used with insulin or other diabetes medications, requiring careful monitoring of blood sugar levels. During treatment, symptoms of reduced fluid volume or low blood pressure may arise, thus regular kidney function tests should be performed, particularly in the elderly or those with compromised kidney function. There is a possibility of genital infections or urinary tract infections, and immediate treatment is necessary if related symptoms appear. This medication may lower vitamin B12 levels; thus, a vitamin B12 check is recommended during long-term use. Excessive alcohol consumption may increase the risk of side effects from this medication, so it should be avoided. If undergoing surgery or imaging tests with contrast agents, consult healthcare professionals and temporarily discontinue this medication. The safety of this medication in children has not been established, and particular caution must be exercised in the elderly regarding decreased kidney function. In case of overdose, seek appropriate medical treatment immediately. Finally, store this medication out of reach of children and in its original container to maintain quality.

Serious side effects

Lactic acidosis, severe hypoglycemia, serious allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness), severe skin reactions (severe rash with fever, blisters, skin peeling, pain in mouth/eye mucous membranes), respiratory issues (shortness of breath or difficulty breathing, asthma attacks, accompanied by cough and fever), liver anomalies (jaundice, yellowing of skin or eyes, extreme lethargy), serious renal problems

Mild side effects

Vulvovaginitis, balanitis, genital infections, urinary tract infections, fungal infections, hypoglycemia, thirst, dizziness, constipation, dry mouth, back pain, dysuria, polyuria, nocturia, vulvar itching, genital itching, increased hematocrit, initial reduction in renal creatinine clearance, dyslipidemia, initial increase in blood creatinine, increase in blood urea, weight loss, diarrhea, nausea/vomiting, reduction/deficiency of vitamin B12, upper abdomen pain

Store this medication in a tightly sealed container to prevent exposure to air and moisture, and keep it at room temperature between 1 to 30 degrees Celsius. Storing it this way will help maintain the medication's effectiveness and prevent degradation.

Appearance

Pink, oval, biconvex, extended-release film-coated tablet

Package unit

30 tablets/box [(6 tablets/PTP)*5], 200 tablets/bottle, 30 tablets/bottle