Sitasingul Tablet 50mg (Sitagliptin Hydrochloride Hydrate)

Adult dosage

This drug is administered once daily at a dose of 100 mg for either monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken independently of meals. For patients with renal impairment, - In mild to moderate renal impairment (eGFR 45 to less than 90), no dosage adjustment is necessary. - In moderate renal impairment (eGFR 30 to less than 45), the dose is 50 mg once daily. - In severe

This drug may cause allergic reactions, so if symptoms such as rash, difficulty breathing, or swelling of the face or neck occur after use, it should be discontinued immediately and medical consultation is necessary. Also, serious inflammation of the pancreas called pancreatitis may occur, so if symptoms such as abdominal pain, vomiting, or persistent nausea are present, medical attention should be sought immediately. This drug should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and should not be administered to those with known hypersensitivity to this drug or its components. Patients with impaired kidney function should have their dosage adjusted, so regular kidney function tests are necessary and the drug should be taken as directed by a physician. Symptoms of hypoglycemia may occur during treatment with this drug, particularly when taken with other antidiabetic medications such as insulin or sulfonylureas, increasing the risk of hypoglycemia. Severe joint pain or blistering skin diseases may occur, so if these symptoms appear, consultation with a physician should be sought immediately. Pregnant or breastfeeding women are advised not to use this drug, and safety and efficacy have not been sufficiently established for children and adolescents under 18 years of age. In case of overdose, one should visit a hospital immediately for appropriate treatment, and this drug can be partially removed through hemodialysis, so hemodialysis may be considered if necessary.

Serious side effects

Urticaria, severe swelling (angioedema), anaphylaxis, severe allergic reactions, Stevens-Johnson syndrome, exfoliative skin disease, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucosa, acute pancreatitis, severe skin adverse reactions, difficulty breathing or dyspnea, asthma attacks, respiratory abnormality accompanied by cough and fever, liver dysfunction (jaundice), increased liver enzyme levels, extreme lethargy, acute renal failure, severe

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• headache
• dyspepsia
• diarrhea
• nausea
• constipation
• myalgia
• limb pain
• back pain

This drug should be stored in a tightly sealed container to prevent air from entering, and it is safe to store at room temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the drug's effectiveness and prevent deterioration.

Appearance

Bright yellow-orange round film-coated tablets

Package unit

Bottle packaging - 100 tablets/bottle, Bottle packaging - 30 tablets/bottle