Pizet Tablet 2/10 mg

Adult dose

This medication is taken once daily, regardless of meals. A starting dose of 2/10 mg once daily is recommended. If the cholesterol-lowering effect on LDL-cholesterol is insufficient, the dose may be increased up to a maximum of 4/10 mg daily. Adjust the dosage appropriately, allowing for intervals of 4 weeks or more. For patients with liver impairment, a starting dose of 1 mg once daily is recommended, with a maximum dose of 2/10 mg daily. Moderate to severe

This drug should not be used in patients who have a known allergy or hypersensitivity to any of its components. Patients with severe liver dysfunction or active liver disease, and patients with persistently elevated liver enzyme levels of unknown cause should also refrain from using this drug. Patients with bile duct obstruction or cholestasis, as well as those receiving cyclosporine, should not be treated with this drug. This medication is also not recommended for patients with myopathy, pregnant women or women who may become pregnant, nursing mothers, and children. Patients with lactose intolerance or related genetic disorders should not take this medication. Patients with mild liver dysfunction or who consume excessive alcohol, patients with renal dysfunction, and those using certain lipid-lowering agents should use this medication cautiously. Elderly patients, patients with hypothyroidism, patients with genetic muscular diseases or a history of muscle issues should also exercise caution. This drug may cause adverse reactions such as myalgia, weakness, or increased liver enzyme levels, so if these symptoms occur, consultation with a doctor should be sought immediately. Additionally, this drug requires regular liver function tests, and administration may be discontinued if liver dysfunction is detected. If symptoms of muscle pain or weakness appear, treatment should be ceased immediately and healthcare providers should be informed, as severe cases can lead to a serious muscle damage condition called rhabdomyolysis. This medication may interact with other drugs, so if other medications are being taken, please inform healthcare providers. Particularly with co-administration of cyclosporine, fibrate medications, or niacin, there is an increased risk of renal function deterioration and muscle damage, thus caution should be exercised. Pregnant women or nursing mothers should not use this medication, and those planning a pregnancy should ensure to consult before taking this drug. It should not be used in children as its safety and efficacy have not been established. In case of overdose, there is no specific antidote, so appropriate treatment and supportive care should be administered based on symptoms, and monitoring of liver function and muscle enzyme levels should be conducted. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

• Urticaria
• chest discomfort
• respiratory difficulties
• rhabdomyolysis
• jaundice
• liver dysfunction
• thrombocytopenia
• increased aminotransferase levels
• hepatitis
• renal function deterioration

Mild side effects

• Abdominal pain
• diarrhea
• dry mouth
• bloating
• gastroesophageal reflux disease
• toothache
• increased alanine aminotransferase
• increased aspartate aminotransferase
• weakness
• chest discomfort

This medication is sensitive to light, so it should be stored in an opaque container that prevents light exposure. Additionally, it is safest to store it at room temperature between 1°C and 30°C. Proper storage will help maintain the drug's effectiveness for a longer duration.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets per bottle