Pevarejet Tablet 2/10 mg

Adult dose

This medication is administered once daily, regardless of meals. The initial recommended dose is 2/10 mg once daily. If the LDL cholesterol-lowering effect is insufficient, the dose may be increased to a maximum of 4/10 mg once daily. For patients with liver dysfunction, the recommended initial dose is 1 mg once daily, so it is not recommended to use this medication at the start of treatment. The maximum dose should be 2/10 mg once daily. For moderate and severe liver dysfunction

This medication should not be used in certain patients. For example, it should not be administered to those with an allergy to its components, patients with severe liver disease, pregnant or nursing women, and children. Patients with impaired liver function or those who consume alcohol excessively should use this medication cautiously, especially patients with poor kidney function also require caution. Furthermore, patients with myopathy or symptoms of muscle weakness and the elderly should be careful when administered. While taking this medication, symptoms such as muscle pain, weakness, and fatigue may appear, so if these symptoms occur, a doctor should be consulted immediately. Regular liver function tests should be done as liver function abnormalities may occur, and if liver enzyme levels rise, the medication may need to be discontinued. This medication can interact with other drugs, so especially when taken with cyclosporine, fibrate drugs, niacin, and certain antibiotics, patients should follow the doctor’s instructions and report any symptoms of muscle pain or worsening kidney function immediately. Pregnant women or women who may become pregnant, as well as nursing mothers, should not use this medication, and if taken during pregnancy, it should be stopped immediately and a doctor consulted. Safety has not been established for use in children, and the elderly should be cautious as the potential for adverse reactions may be higher. In case of overdose, there is no specific antidote, so treatment should be symptomatic and supportive therapy should be provided while monitoring liver function and muscle enzyme levels. This medication should be stored out of the reach of children and not transferred to another container.

Serious side effects

Urticaria, chest discomfort, thrombocytopenia, rhabdomyolysis, liver dysfunction, jaundice, severe allergic reaction, acute renal impairment accompanying severe kidney dysfunction, severe muscle weakness or ocular myasthenia, interstitial lung disease, persistent increase in aminotransferase levels, immune-mediated necrotizing myopathy, acute renal failure, severe edema, high blood pressure, chest tightness, difficulty breathing, headache, paralysis, visual disturbances, altered consciousness

Mild side effects

• Abdominal pain
• diarrhea
• dry mouth
• bloating
• gastroesophageal reflux disease
• toothache
• weakness
• fatigue
• muscle pain
• taste disturbance

This medication should be stored in a container that blocks light and air, and it is safe to store at room temperature between 1 degree and 30 degrees Celsius. Therefore, it should be kept away from direct sunlight and in a place that is neither too hot nor too cold.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle